Stable isotope labeling by fatty acids in cell culture (SILFAC) coupled with isotope pattern dependent mass spectrometry for global screening of lipid hydroperoxide-mediated protein modifications.
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DOI: 10.1016/j.jprot.2017.07.006
Abstract: Lipid hydroperoxide-mediated modifications of proteins are receiving increasing attention because of their possible involvement in various degenerative diseases. These biological effects are attributed to the ability of lipid peroxidation-derived aldehydes to react with the nucleophilic… read more here.
Keywords: methodology; isotope; hydroperoxide mediated; lipid hydroperoxide ... See more keywords