Association of Lipid-Lowering Drugs With Risk of Psoriasis: A Mendelian Randomization Study.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.6051
Abstract: Importance Lipid pathways have been implicated in the pathogenesis of psoriasis, and some lipid-lowering drugs, such as statins, are hypothesized to have disease-modifying properties. However, large population-level studies are scarce, and causal interpretation of results… read more here.
Keywords: lowering drugs; risk psoriasis; lipid lowering; risk ... See more keywords
Participation of Women and Older Participants in Randomized Clinical Trials of Lipid-Lowering Therapies
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.5202
Abstract: Key Points Question Are women and older participants adequately represented in randomized clinical trials of lipid-lowering therapy? Findings In this systematic review of 60 trials with 485 409 participants that were conducted between 1990 and 2018,… read more here.
Keywords: trials lipid; older participants; women older; randomized clinical ... See more keywords
Temporal Changes in Obesity-Related Medication After Bariatric Surgery vs No Surgery for Obesity.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA surgery"
DOI: 10.1001/jamasurg.2023.0252
Abstract: Importance Bariatric surgery can resolve hyperlipidemia, cardiovascular disease, and diabetes, but the long-term postoperative trajectories of medications for these conditions are unknown. Objective To clarify the long-term use of lipid-lowering, cardiovascular, and antidiabetic medication after… read more here.
Keywords: medication; surgery; obesity; lipid lowering ... See more keywords
Influence of intensive lipid‐lowering on CT derived fractional flow reserve in patients with stable chest pain: Rationale and design of the FLOWPROMOTE study
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Cardiology"
DOI: 10.1002/clc.23895
Abstract: Coronary CT angiography (CTA) derived fractional flow reserve (FFRCT) shows high diagnostic performance when compared to invasively measured FFR. Presence and extent of low attenuation plaque density have been shown to be associated with abnormal… read more here.
Keywords: derived fractional; physiology; lipid lowering; fractional flow ... See more keywords
Guggulsterone, a Classical Lipid-Lowering Phytosteroidal FXR Antagonist, as a Modulator of Lipid Signaling and Metabolic Reprogramming in Cancer.
Sign Up to like & getrecommendations! Published in 2025 at "Lipids"
DOI: 10.1002/lipd.70030
Abstract: Dysregulated lipid metabolism fuels cancer progression through enhanced lipogenesis, cholesterol synthesis, and fatty acid oxidation. Herbal bioactives provide multi-targeted molecular interventions capable of restoring lipid homeostasis while minimizing toxicity. Guggulsterone (GS), a plant-derived steroidal compound… read more here.
Keywords: cancer; metabolic reprogramming; lipid lowering; lipid signaling ... See more keywords
2-Hydroxy-4-methoxy benzoic acid attenuates the carbon tetra chloride-induced hepatotoxicity and its lipid abnormalities in rats via anti-inflammatory and antioxidant mechanism
Sign Up to like & getrecommendations! Published in 2017 at "Inflammation Research"
DOI: 10.1007/s00011-017-1054-2
Abstract: Background and aimLiver inflammation stimulates various inflammatory cytokines and initiates injury through oxidative stress. The aim of this study was to curtaile the liver injury through natural principles such as 2-hydroxy-4-methoxy benzoic acid (HMBA).MethodsThe current… read more here.
Keywords: tetra chloride; methoxy benzoic; carbon tetra; benzoic acid ... See more keywords
Hyperlipidaemia in diabetes: are there particular considerations for next-generation therapies?
Sign Up to like & getrecommendations! Published in 2024 at "Diabetologia"
DOI: 10.1007/s00125-024-06100-z
Abstract: Dyslipidaemias are major cardiovascular risk factors, especially in people with diabetes. In this area, next-generation therapies targeting circulating lipoparticle metabolism (LDL, VLDL, chylomicrons, HDL) have recently been approved by the European and US medical agencies,… read more here.
Keywords: next generation; risk; lipid lowering; people diabetes ... See more keywords
Do acute coronary events affect lipid management and cholesterol goal attainment in Germany?
Sign Up to like & getrecommendations! Published in 2018 at "Wiener Klinische Wochenschrift"
DOI: 10.1007/s00508-018-1375-3
Abstract: SummaryObjectiveTo document utilization of lipid-lowering therapy, attainment of low-density lipoprotein cholesterol target values, and cardiovascular outcomes in patients hospitalized for acute coronary syndrome in Germany.MethodsThe Dyslipidemia International Study II was a multicenter, observational study of the prevalence… read more here.
Keywords: lowering therapy; density lipoprotein; cholesterol; acute coronary ... See more keywords
Lipid lowering therapy in primary and secondary prevention in Austria: are LDL-C goals achieved?
Sign Up to like & getrecommendations! Published in 2021 at "Wiener klinische Wochenschrift"
DOI: 10.1007/s00508-021-01978-w
Abstract: Cardiovascular disease (CVD) is the most frequent cause of death in Austria. The European Society of Cardiology (ESC)/European Atherosclerosis Society (EAS) guidelines recommend intensive lipid lowering therapy (LLT) in patients at high or very high… read more here.
Keywords: lipid lowering; therapy; primary secondary; intensity ... See more keywords
Lipid-Lowering Biotechnological Drugs: from Monoclonal Antibodies to Antisense Therapies—a Clinical Perspective
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-020-07082-x
Abstract: While low density lipoprotein cholesterol (LDL-C) remains a key contributor of atherosclerotic cardiovascular disease (ASCVD), additional risk factors identified through epidemiological and genetic studies have ushered in a fertile era of drug discovery in lipid-lowering… read more here.
Keywords: risk; biotechnological drugs; risk factors; clinical trials ... See more keywords
Preferences for Injectable Lipid-Lowering Therapies in Japanese Patients with Atherosclerotic Cardiovascular Disease: Findings from a Japanese Cross-sectional Study
Sign Up to like & getrecommendations! Published in 2025 at "Advances in Therapy"
DOI: 10.1007/s12325-025-03321-5
Abstract: Understanding patient preferences for injectable lipid-lowering therapies (LLTs) is crucial for optimizing adherence and outcomes for preventing atherosclerotic cardiovascular diseases (ASCVDs). This study aimed to quantify patient preferences for injectable LLTs among Japanese patients with… read more here.
Keywords: disease; injectable lipid; history; lipid lowering ... See more keywords