Lipid-mediated impairment of axonal lysosome transport contributing to autophagic stress
Sign Up to like & getrecommendations! Published in 2021 at "Autophagy"
DOI: 10.1080/15548627.2021.1938916
Abstract: ABSTRACT Efficient degradation of autophagic vacuoles (AVs) generated at axon terminals by mature lysosomes enriched in the cell body represents an exceptional challenge that neurons face in maintaining cellular homeostasis. Here, we discuss our recent… read more here.
Keywords: autophagic stress; lipid mediated; lysosome transport; mediated impairment ... See more keywords
Lipid-mediated regulation of pro-inflammatory responses induced by lipopolysaccharide.
Sign Up to like & getrecommendations! Published in 2018 at "Postepy biochemii"
DOI: 10.18388/pb.2018_129
Abstract: Lipopolysaccharide (LPS, endotoxin) is the component of the outer membrane of Gramnegative bacteria which upon infection induces the body's inflammatory reaction facilitating eradication of pathogens. However, exaggerated reactions to LPS can lead to potentially deadly… read more here.
Keywords: regulation pro; inflammatory responses; mediated regulation; lipid mediated ... See more keywords