Lipid Mediator Quantification in Isolated Human and Guinea Pig Airways: An Expanded Approach for Respiratory Research.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b01651
Abstract: The clinical importance of prostaglandins and leukotrienes in asthma is well recognized; however, the biochemical role of other lipid mediators (often termed oxylipins) in the regulation of airway tone and inflammation remains unclear. We therefore… read more here.
Keywords: guinea; guinea pig; lipid mediator; human bronchus ... See more keywords
Immunomodulatory lipid mediator profiling of cerebrospinal fluid following surgery in older adults
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82606-5
Abstract: Arachidonic acid (AA), docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA) derived lipids play key roles in initiating and resolving inflammation. Neuro-inflammation is thought to play a causal role in perioperative neurocognitive disorders, yet the role… read more here.
Keywords: dha epa; lipid mediator; centrifuged csf; older adults ... See more keywords
Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.16673
Abstract: Degradation of lysosomal lipids requires lysosomal acid lipase (LAL), the only intracellular lipase known to be active at acidic pH. We found LAL to be expressed in murine immune cells with highest mRNA expression in… read more here.
Keywords: lal; lipid mediator; mediator synthesis; lipid hydrolysis ... See more keywords
The Trace Element Selenium Is Important for Redox Signaling in Phorbol Ester-Differentiated THP-1 Macrophages
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DOI: 10.3390/ijms222011060
Abstract: Physiological selenium (Se) levels counteract excessive inflammation, with selenoproteins shaping the immunoregulatory cytokine and lipid mediator profile. How exactly differentiation of monocytes into macrophages influences the expression of the selenoproteome in concert with the Se… read more here.
Keywords: lipid mediator; phorbol; expression; differentiation ... See more keywords
Phytochemical Characterization of Cannabis sativa L. Chemotype V Reveals Three New Dihydrophenanthrenoids That Favorably Reprogram Lipid Mediator Biosynthesis in Macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants11162130
Abstract: The growing general interest surrounding Cannabis sativa L. has led to a renewal in breeding and resulted in an impressive variability of chemotypical characteristics that required the division of cannabis into different recognized chemotypes. The… read more here.
Keywords: sativa chemotype; cannabis sativa; chemotype; lipid mediator ... See more keywords