Dimethyl fumarate treatment induces lipid metabolism alterations that are linked to immunological changes
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.676
Abstract: Identify metabolic changes produced by dimethyl fumarate (DMF) treatment and link them to immunological effects. read more here.
Keywords: induces lipid; lipid metabolism; treatment; treatment induces ... See more keywords
Platelet‐Derived Growth Factor C Facilitates Malignant Behavior of Pancreatic Ductal Adenocarcinoma by Regulating SREBP1 Mediated Lipid Metabolism
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202407069
Abstract: Lipid metabolism reprogramming stands as a fundamental hallmark of cancer cells. Unraveling the core regulators of lipid biosynthesis holds the potential to find promising therapeutic targets in pancreatic ductal adenocarcinoma (PDAC). Here, it is demonstrated… read more here.
Keywords: lipid metabolism; factor; pdgfc; srebp1 ... See more keywords
The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma
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DOI: 10.1002/advs.202501774
Abstract: Metabolic reprogramming is a hallmark of cancer, with dysregulated lipid metabolism contributing to tumor progression and therapy resistance. This study identifies the DNA demethylase TET3 as a key regulator of lipogenic metabolism in pancreatic ductal… read more here.
Keywords: ductal adenocarcinoma; lipid metabolism; tet3 gata6; metabolism ... See more keywords
Characterization of Triacylglycerol Dynamics and Lipid Metabolism in the Beetle Tribolium castaneum.
Sign Up to like & getrecommendations! Published in 2025 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.70111
Abstract: Lipids are essential for all organisms, and insects can obtain these macromolecules from their diet or synthesize them from carbohydrates and amino acids. These animals store fatty acids in the form of triacylglycerol in lipid… read more here.
Keywords: lipid metabolism; beetle tribolium; triacylglycerol; castaneum ... See more keywords
Lipid metabolism in pancreatic cancer: emerging roles and potential targets
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DOI: 10.1002/cac2.12360
Abstract: Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently read more here.
Keywords: pancreatic cancer; metabolism pancreatic; lipid metabolism; cancer emerging ... See more keywords
Suppression of ABCD2 dysregulates lipid metabolism via dysregulation of miR‐141:ACSL4 in human osteoarthritis
Sign Up to like & getrecommendations! Published in 2018 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3356
Abstract: Even though increasing evidence indicates the importance of peroxisomal lipid metabolism in regulating biological and pathological events, its involvement in cartilage development has not been well studied. Here, we identified the importance of peroxisomal function,… read more here.
Keywords: suppression; metabolism; acsl4 human; osteoarthritis ... See more keywords
Microbial creation of β‐Nicotinamide mononucleotide and its regulation of lipid metabolism in the liver of high‐fat diet mice
Sign Up to like & getrecommendations! Published in 2024 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.4087
Abstract: β‐Nicotinamide mononucleotide (NMN) is a biologically active nucleotide that regulates the physiological metabolism of the body by rapidly increasing nicotinamide adenine dinucleotide (NAD+). To determine the safety and biological activity of NMN resources, we constructed… read more here.
Keywords: nicotinamide mononucleotide; lipid metabolism; fat diet; metabolism ... See more keywords
Anoikis in cancer: The role of lipid signaling
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DOI: 10.1002/cbin.11896
Abstract: Malignantly transformed cells must alter their metabolic status to stay viable in a harsh microenvironment and maintain their ability to invade and spread. Anoikis, a specific detachment‐related form of apoptotic cell death, is a potential… read more here.
Keywords: metabolism; cancer role; lipid metabolism; role lipid ... See more keywords
New Glance at the Role of TM6SF2 in Lipid Metabolism and Liver Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.31851
Abstract: Non-alcoholic fatty liver disease (NAFLD) is rapidly becoming the most common cause of chronic liver diseases. NAFLD can progress to more severe conditions, such as non-alcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma (HCC), which confer… read more here.
Keywords: metabolism liver; tm6sf2 lipid; new glance; role tm6sf2 ... See more keywords
Cadmium exposure induces endothelial dysfunction via disturbing lipid metabolism in human microvascular endothelial cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4115
Abstract: Cadmium (Cd) is an occupational and environmental heavy metal pollutant derived from many sources that is linked to endothelial homeostasis. The endothelium is an important site of Cd deposition, while increasing evidence has revealed there… read more here.
Keywords: dysfunction; exposure; endothelial cells; lipid metabolism ... See more keywords
Mechanisms of di (2‐Ethylhexyl) Phthalate‐Induced Lipid Metabolism Disorders: A Review
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4867
Abstract: Di(2‐ethylhexyl) phthalate (DEHP) is a widely used plasticizer that can be absorbed by the human body through various pathways. Numerous studies have indicated the adverse effects of DEHP on lipid metabolism. Experimental and population studies… read more here.
Keywords: induced lipid; lipid metabolism; metabolism disorders; metabolism ... See more keywords