Wnt/Wingless signaling promotes lipid mobilization through signal-induced transcriptional repression
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2322066121
Abstract: Significance The Wnt signaling pathway, often deregulated in cancer and other diseases, remains poorly understood in lipid metabolism, particularly lipid mobilization. This study reveals that active Wnt/Wg signaling potently reduces lipid accumulation in Drosophila adipocytes… read more here.
Keywords: wnt; transcriptional repression; induced transcriptional; wnt signaling ... See more keywords
SCD1 promotes lipid mobilization in subcutaneous white adipose tissue.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of lipid research"
DOI: 10.1194/jlr.ra120000869
Abstract: Beiging of white adipose tissue (WAT) has beneficial effects on metabolism. Although it is known that beige adipocytes are active in lipid catabolism and thermogenesis, how they are regulated deserves more explorations. In this study,… read more here.
Keywords: adipose tissue; white adipose; scd1; lipid mobilization ... See more keywords
Redox Regulation of Lipid Mobilization in Adipose Tissues
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DOI: 10.3390/antiox10071090
Abstract: Lipid mobilization in adipose tissues, which includes lipogenesis and lipolysis, is a paramount process in regulating systemic energy metabolism. Reactive oxygen and nitrogen species (ROS and RNS) are byproducts of cellular metabolism that exert signaling… read more here.
Keywords: mobilization adipose; adipose tissues; lipolysis; lipid mobilization ... See more keywords
Essential Oil of Carvone Chemotype Lippia alba (Verbenaceae) Regulates Lipid Mobilization and Adipogenesis in Adipocytes
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DOI: 10.3390/cimb44110389
Abstract: Obesity is characterized by an expansion of adipose tissue due to excessive accumulation of triglycerides in adipocytes, causing hypertrophy and hyperplasia, followed by hypoxia, alterations in adipocyte functionality, and chronic inflammation. However, current treatments require… read more here.
Keywords: carvone chemotype; carvone; mobilization adipogenesis; lipid mobilization ... See more keywords