Predicting phototoxicity of alkylated PAHs, mixtures of PAHs, and water accommodated fractions (WAF) of neat and weathered petroleum with the phototoxic target lipid model.
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DOI: 10.1002/etc.4173
Abstract: The toxicity of petroleum can increase considerably after exposure to solar radiation, during which certain components in the mixture, including polycyclic aromatic hydrocarbons (PAHs), absorb light in ultraviolet and visible portions of the solar radiation… read more here.
Keywords: alkylated pahs; target lipid; phototoxic target; lipid model ... See more keywords
Novel non-helical antimicrobial peptides insert into and fuse lipid model membranes
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DOI: 10.1039/d4sm00220b
Abstract: This research addresses the growing menace of antibiotic resistance by exploring antimicrobial peptides (AMPs) as alternatives to conventional antibiotics. Specifically, we investigate two linear amphipathic AMPs, LE-53 (12-mer) and LE-55 (16-mer), finding that the shorter… read more here.
Keywords: model membranes; lipid model; non helical; novel non ... See more keywords
Acute-to-chronic ratios of aquatic phototoxicity of polycyclic aromatic hydrocarbons and the prediction of chronic phototoxicity using the phototoxic target lipid model.
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DOI: 10.1093/etojnl/vgae069
Abstract: Polycyclic aromatic hydrocarbons (PAHs) are a group of organic compounds that can be toxic to aquatic life at environmentally relevant concentrations. The toxicity of some PAHs increases in the presence of ultraviolet radiation (UVR). The… read more here.
Keywords: lipid model; phototoxicity; target lipid; acute chronic ... See more keywords
Analysis of Metabolite Distribution in Rat Liver of High-Fat Model by Mass Spectrometry Imaging
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DOI: 10.3390/metabo13030411
Abstract: Hyperlipidemia is a medical condition characterized by elevated levels of blood lipids, especially triglycerides (TG). However, it remains unclear whether TG levels remain consistently elevated throughout the entire developmental stage of the high-lipid state. In… read more here.
Keywords: high lipid; spectrometry imaging; lipid model; mass spectrometry ... See more keywords