Optimization of Lipid Nanoformulations for Effective mRNA Delivery
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s363990
Abstract: Introduction Since the coronavirus disease 2019 (COVID-19) pandemic, the value of mRNA vaccine has been widely recognized worldwide. Messenger RNA (mRNA) therapy platform provides a promising alternative to DNA delivery in non-viral gene therapy. Lipid… read more here.
Keywords: mrna delivery; optimization lipid; lipid nanoformulations; delivery ... See more keywords
Hybrid Lipid Nanoformulations for Hepatoma Therapy: Sorafenib Loaded Nanoliposomes—A Preliminary Study
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DOI: 10.3390/nano12162833
Abstract: Sorafenib is a multikinase inhibitor that has received increasing attention due to its high efficacy in hepatocellular carcinoma treatment. However, its poor pharmacokinetic properties (limited water solubility, rapid elimination, and metabolism) still represent major bottlenecks… read more here.
Keywords: nanoformulations hepatoma; sorafenib loaded; loaded nanoliposomes; hybrid lipid ... See more keywords