Phospholipidic Colchicinoids as Promising Prodrugs Incorporated into Enzyme-Responsive Liposomes: Chemical, Biophysical, and Enzymological Aspects.
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DOI: 10.1021/acs.bioconjchem.9b00051
Abstract: Enzyme-responsive liposomes release their cargo in response to pathologically increased levels of enzymes at the target site. We report herein an assembly of phospholipase A2-responsive liposomes based on colchicinoid lipid prodrugs incorporated into lipid bilayer… read more here.
Keywords: lipid prodrugs; responsive liposomes; enzyme responsive; colchicinoids promising ... See more keywords