Serotonin Transporter Regulation by Cholesterol-Independent Lipid Signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.114349
Abstract: Serotonin neurotransmission is largely governed by the regulation of the serotonin transporter (SERT). SERT is modulated in part by cholesterol, but the role of cholesterol and lipid signaling intermediates in regulating SERT are unknown. Serotonergic… read more here.
Keywords: serotonin transporter; lipid signaling; cholesterol; cholesterol independent ... See more keywords
A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental cell"
DOI: 10.1016/j.devcel.2018.02.025
Abstract: Phosphatidylinositol (PtdIns) transfer proteins (PITPs) stimulate PtdIns-4-P synthesis and signaling in eukaryotic cells, but to what biological outcomes such signaling circuits are coupled remains unclear. Herein, we show that two highly related StART-like PITPs, PITPNA… read more here.
Keywords: pathway controls; golgi; lipid signaling; signaling pathway ... See more keywords
Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.08.038
Abstract: The Hippo pathway plays a crucial role in organ size control and tumor suppression, but its precise regulation is not fully understood. In this study, we discovered that phosphatidic acid (PA)-related lipid signaling is a… read more here.
Keywords: lipid signaling; regulation hippo; pathway phosphatidic; phosphatidic acid ... See more keywords
Lipid signaling and fat storage in the dark-eyed junco.
Sign Up to like & getrecommendations! Published in 2017 at "General and comparative endocrinology"
DOI: 10.1016/j.ygcen.2017.01.029
Abstract: Seasonal hyperphagia and fattening promote survivorship in migratory and wintering birds, but reduced adiposity may be more advantageous during the breeding season. Factors such as photoperiod, temperature, and food predictability are known environmental determinants of… read more here.
Keywords: storage; junco; fat storage; signaling fat ... See more keywords
The Road to Quantitative Lipid Biochemistry in Living Cells
Sign Up to like & getrecommendations! Published in 2023 at "Accounts of Chemical Research"
DOI: 10.1021/acs.accounts.2c00804
Abstract: Conspectus Traditional cell biological techniques are not readily suitable for studying lipid signaling events because genetic perturbations are much slower than the interconversion of lipids in complex metabolic networks. For this reason, novel chemical biological… read more here.
Keywords: lipid signaling; caged compounds; living cells; biochemistry ... See more keywords
Parasitic nematode fatty acid- and retinol-binding proteins compromise host immunity by interfering with host lipid signaling pathways
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010027
Abstract: Parasitic nematodes cause significant morbidity and mortality globally. Excretory/secretory products (ESPs) such as fatty acid- and retinol- binding proteins (FARs) are hypothesized to suppress host immunity during nematode infection, yet little is known about their… read more here.
Keywords: immunity; retinol binding; acid retinol; fatty acid ... See more keywords
Mitochondrial Lipid Signaling and Adaptive Thermogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Metabolites"
DOI: 10.3390/metabo11020124
Abstract: Thermogenesis is an energy demanding process by which endotherms produce heat to maintain their body temperature in response to cold exposure. Mitochondria in the brown and beige adipocytes play a key role in thermogenesis, as… read more here.
Keywords: thermogenesis; signaling adaptive; lipid signaling; mitochondrial lipid ... See more keywords
Deciphering Complex Interactions in Bioactive Lipid Signaling
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28062622
Abstract: Lipids are usually viewed as metabolic fuel and structural membrane components. Yet, in recent years, different families of lipids able to act as authentic messengers between cells and/or intracellularly have been discovered. Such lipid signals… read more here.
Keywords: lipid signaling; interactions bioactive; bioactive lipid; complex interactions ... See more keywords