Model lipid systems and their use to evaluate the phase state of biomembranes, their mechanical properties and the effect of non-conventional antibiotics: the case of daptomycin
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DOI: 10.1007/s00249-020-01445-w
Abstract: The lipid bilayer is the basis of the structure and function of the cell membrane. The study of the molecular phenomena that affect biological membranes has a great impact on the understanding of cellular physiology.… read more here.
Keywords: phase; systems use; effect; model ... See more keywords
Normalizing Polydiacetylene Colorimetric Assays of Vesicle Binding Across Lipid Systems.
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DOI: 10.1016/j.ab.2020.113864
Abstract: Mixed polydiacetylene (PDA) lipid vesicles mimic cell membranes and exhibit a colorimetric response induced by mechanical stress, which can be used to determine the affinity of proteins or molecules for lipid membranes. Due to a… read more here.
Keywords: polydiacetylene colorimetric; normalizing polydiacetylene; colorimetric assays; assays vesicle ... See more keywords
Toward simplified oral lipid-based drug delivery using mono-/di-glycerides as single component excipients
Sign Up to like & getrecommendations! Published in 2020 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2020.1843475
Abstract: Abstract Objective This study aimed to systematically explore compositional effects for a series of lipid systems, on the in vitro drug solubilization and in vivo bioavailability of three poorly water-soluble drugs with different physico-chemical properties.… read more here.
Keywords: component; lipid based; drug; single component ... See more keywords