Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16696-6
Abstract: Inherited peripheral neuropathies (IPNs) represent a broad group of disorders including Charcot-Marie-Tooth (CMT) neuropathies characterized by defects primarily arising in myelin, axons, or both. The molecular mechanisms by which mutations in nearly 100 identified IPN/CMT… read more here.
Keywords: lipid turnover; rab35; mtorc1; growth ... See more keywords
DO‐SRS imaging of diet regulated metabolic activities in Drosophila during aging processes
Sign Up to like & getrecommendations! Published in 2022 at "Aging Cell"
DOI: 10.1111/acel.13586
Abstract: Lipid metabolism plays crucial roles during aging processes, but how it is regulated by diets and how it interplays with aging still remain unclear. We proposed a new optical imaging platform by integrating heavy water… read more here.
Keywords: lipid turnover; signaling pathway; lipid metabolism; insulin signaling ... See more keywords