A Tunable Microfluidic Device Enables Cargo Encapsulation by Cell‐ or Organelle‐Sized Lipid Vesicles Comprising Asymmetric Lipid Bilayers
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Biosystems"
DOI: 10.1002/adbi.201900010
Abstract: Cellular membranes play host to a wide variety of morphologically and chemically complex processes. Although model membranes, like liposomes, are already widely used to reconstitute and study these processes, better tools are needed for making… read more here.
Keywords: asymmetric lipid; tunable microfluidic; organelle sized; lipid vesicles ... See more keywords
Using Holographic Microscopy To Measure the Effect of Confinement on Crowding Agents in Lipid Vesicles
Sign Up to like & getrecommendations! Published in 2023 at "ChemBioChem"
DOI: 10.1002/cbic.202300069
Abstract: The hydrodynamic effects of macromolecular crowding inside cells are often studied in vitro by using polymers as crowding agents. Confinement of polymers inside cell‐sized droplets has been shown to affect the diffusion of small molecules. Here… read more here.
Keywords: lipid vesicles; crowding agents; microscopy measure; confinement crowding ... See more keywords
Effect of Packing Density of Lipid Vesicles on the Aβ42 Fibril Polymorphism.
Sign Up to like & getrecommendations! Published in 2021 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2021.105073
Abstract: The aggregation of amyloid-β 1-42 (Aβ42) on lipid membranes is closely related to the pathology of Alzheimer's disease (AD). Herein, we demonstrated the effect of the packing density of lipid vesicles on the Aβ42 fibrillation… read more here.
Keywords: density lipid; packing density; density; lipid vesicles ... See more keywords
Extracellular Cues Govern Shape and Cytoskeletal Organization in Giant Unilamellar Lipid Vesicles
Sign Up to like & getrecommendations! Published in 2023 at "ACS Synthetic Biology"
DOI: 10.1021/acssynbio.2c00516
Abstract: Spontaneous and induced front-rear polarization and a subsequent asymmetric actin cytoskeleton is a crucial event leading to cell migration, a key process involved in a variety of physiological and pathological conditions such as tissue development,… read more here.
Keywords: lipid vesicles; unilamellar lipid; organization; cytoskeleton ... See more keywords
Geometric pinning and antimixing in scaffolded lipid vesicles
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-17432-w
Abstract: Previous studies on the phase behaviour of multicomponent lipid bilayers found an intricate interplay between membrane geometry and its composition, but a fundamental understanding of curvature-induced effects remains elusive. Thanks to a combination of experiments… read more here.
Keywords: antimixing scaffolded; scaffolded lipid; geometric pinning; pinning antimixing ... See more keywords
Controlled shaping of lipid vesicles in a microfluidic diffusion chamber
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra05584f
Abstract: Synthetic lipid vesicles represent an important model system for studying membrane processes, which often depend on membrane shape, but controlled shaping of vesicles remains a challenging experimental task. Here, we present a novel method for… read more here.
Keywords: diffusion chamber; diffusion; microfluidic diffusion; lipid vesicles ... See more keywords
Limiting shapes of confined lipid vesicles.
Sign Up to like & getrecommendations! Published in 2019 at "Soft matter"
DOI: 10.1039/c8sm01956h
Abstract: We theoretically study the shapes of lipid vesicles confined to a spherical cavity, elaborating a framework based on the so-called limiting shapes constructed from geometrically simple structural elements such as double-membrane walls and edges. Partly… read more here.
Keywords: confined lipid; shapes confined; lipid vesicles; limiting shapes ... See more keywords
Changes in membrane elasticity caused by the hydrophobic surfactant proteins correlate poorly with adsorption of lipid vesicles.
Sign Up to like & getrecommendations! Published in 2021 at "Soft matter"
DOI: 10.1039/d0sm02223c
Abstract: To establish how the hydrophobic surfactant proteins, SP-B and SP-C, promote adsorption of lipids to an air/water interface, we used X-ray diffuse scattering (XDS) to determine an order parameter of the lipid chains (Sxray) and… read more here.
Keywords: adsorption; hydrophobic surfactant; proteins produced; adsorption lipid ... See more keywords
Sensing and manipulating single lipid vesicles using dynamic DNA nanotechnology.
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d2nr07192d
Abstract: Natural and artificial lipid vesicles have been widely involved in nano-delivery, bio-analysis and diagnosis. For sensing and manipulating single lipid vesicles, dynamic DNA reactions were constructed inside or on the surface of lipid vesicles. In… read more here.
Keywords: lipid vesicles; manipulating single; nanotechnology; sensing manipulating ... See more keywords
Protein corona alters the mechanisms of interaction between silica nanoparticles and lipid vesicles.
Sign Up to like & getrecommendations! Published in 2022 at "Soft matter"
DOI: 10.1039/d2sm00739h
Abstract: The use of nanoparticles (NPs) for biomedical applications implies their delivery into the organism where they encounter biological fluids. In such biological fluids, proteins and other biomolecules adhere to the surface of the NPs forming… read more here.
Keywords: interaction; lipid vesicles; silica nanoparticles; nanoparticles lipid ... See more keywords
Modulation of wetting of stimulus responsive polymer brushes by lipid vesicles: experiments and simulations.
Sign Up to like & getrecommendations! Published in 2023 at "Soft matter"
DOI: 10.1039/d2sm01673g
Abstract: The interactions between vesicle and substrate have been studied by simulation and experiment. We grafted polyacrylic acid brushes containing cysteine side chains at a defined area density on planar lipid membranes. Specular X-ray reflectivity data… read more here.
Keywords: interaction range; adhesion; lipid vesicles; modulation wetting ... See more keywords