Coated Lipidic Nanoparticles as a New Strategy for Enhancing Nose-to-Brain Delivery of a Hydrophilic Drug Molecule.
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DOI: 10.1016/j.xphs.2020.04.007
Abstract: Oral Almotriptan maleate (ALM) is used in the treatment of migraine; however, due to its extreme aqueous solubility, shows poor penetration and lesser concentration in the brain thus requiring frequent oral dosing. Being flexible and… read more here.
Keywords: coated lipidic; lipidic nanoparticles; drug; nanoparticles new ... See more keywords