Identifying mitotane-induced mitochondria-associated membranes dysfunctions: metabolomic and lipidomic approaches
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.18968
Abstract: Mitotane (o,p’DDD), the most effective drug in adrenocortical carcinoma, concentrates into the mitochondria and impacts mitochondrial functions. To address the molecular mechanisms of mitotane action and to identify its potential target, metabolomic and lipidomic approaches… read more here.
Keywords: lipidomic approaches; mitotane; mitochondria associated; mitotane induced ... See more keywords
Metabolomic and lipidomic approaches to identify biomarkers for bladder cancer and interstitial cystitis
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2020.11627
Abstract: The discovery, introduction and clinical use of prognostic and diagnostic biomarkers has significantly improved outcomes for patients with various illnesses, including bladder cancer (BC) and other bladder-related diseases, such as benign bladder dysfunction and interstitial… read more here.
Keywords: lipidomic approaches; bladder cancer; interstitial cystitis; metabolomic lipidomic ... See more keywords