Articles with "lipidomic profiling" as a keyword



Lipidomic profiling of exosomes from colorectal cancer cells and patients reveals potential biomarkers

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Published in 2022 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13223

Abstract: Strong evidence suggests that differences in the molecular composition of lipids in exosomes depend on the cell type and has an influence on cancer initiation and progression. Here, we analyzed by liquid chromatography–mass spectrometry (LC‐MS)… read more here.

Keywords: potential biomarkers; cell; lipidomic profiling; colorectal cancer ... See more keywords
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Comparative Primary Metabolic and Lipidomic Profiling of Freshwater and Marine Synechocystis Strains Using by GC-MS and NanoESI-MS Analyses

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Published in 2020 at "Biotechnology and Bioprocess Engineering"

DOI: 10.1007/s12257-019-0432-8

Abstract: Synechocystis strains are considered as valuable resources for production of useful metabolites. Comparative primary metabolic and lipidomic profiling of freshwater and marine Synechocystis strains is needed to understand the physiological characteristics of each strain at… read more here.

Keywords: primary metabolic; metabolic lipidomic; comparative primary; lipidomic profiling ... See more keywords

Lipidomic profiling of dairy cattle oocytes by high performance liquid chromatography-high resolution tandem mass spectrometry for developmental competence markers.

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Published in 2019 at "Theriogenology"

DOI: 10.1016/j.theriogenology.2019.11.039

Abstract: A comparative lipidomic profiling analysis of dairy cattle oocytes with different developmental competences was performed using a combination of high performance liquid chromatography-high resolution tandem mass spectrometry and multivariate statistical analysis. Significant lipidomic changes were… read more here.

Keywords: developmental competence; lipidomic profiling; dairy cattle; pmol ... See more keywords

Lipidomic Profiling of Metastatic Lung Cancer-Derived Exosomes Unveiling Ceramides as Potential Biomarkers by Supramolecular Probe Enrichment and Mass Spectrometry Analysis.

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Published in 2025 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.5c02746

Abstract: Tumor-derived exosomes play a crucial role in intercellular communication, significantly influencing cancer metastatic progression. Nonsmall cell lung cancer (NSCLC), the primary cause of cancer-related mortality in solid tumors worldwide, is particularly notorious for its poor… read more here.

Keywords: cancer; lung cancer; derived exosomes; supramolecular probe ... See more keywords

Lipidomic Profiling of Red Blood Cells in the Mitochondrial Fatty Acid β-oxidation Disorder MCADD Reveals Phospholipid and Sphingolipid Dysregulation.

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Published in 2025 at "Journal of proteome research"

DOI: 10.1021/acs.jproteome.5c00308

Abstract: Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is characterized by the accumulation of medium-chain acylcarnitines. Despite the therapeutic approach, changes in lipid homeostasis have been reported in MCADD plasma samples. Compared to plasma lipidomics, red blood cell… read more here.

Keywords: mcadd; profiling red; blood cells; blood ... See more keywords

UPLC- QTOF - MS Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis.

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Published in 2019 at "Journal of proteome research"

DOI: 10.1021/acs.jproteome.9b00440

Abstract: Identification of new biomarkers may help to early diagnosis of inflammatory bowel disease (IBD). In this study, ultra-high-performance liquid chromatography equipped with quadrupole time-of-flight mass spectrometry (UPLC - QTOF - MS) were used to analyze… read more here.

Keywords: bowel disease; diagnosis; inflammatory bowel; uplc qtof ... See more keywords
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Lipidomic profiling reveals distinct differences in plasma lipid composition in healthy, prediabetic, and type 2 diabetic individuals

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Published in 2017 at "GigaScience"

DOI: 10.1093/gigascience/gix036

Abstract: Abstract The relationship between dyslipidemia and type 2 diabetes mellitus (T2D) has been extensively reported, but the global lipid profiles, especially in the East Asia population, associated with the development of T2D remain to be… read more here.

Keywords: reveals distinct; profiling reveals; distinct differences; plasma lipid ... See more keywords

Lipidomic profiling and skincare potential of rice bran fermented by Lacticaseibacillus casei M8 and yeast

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Published in 2025 at "International Journal of Food Science and Technology"

DOI: 10.1093/ijfood/vvaf121

Abstract: Ceramide (Cer), a preferred moisturizer, faces challenges related to extraction efficiency and safety issues linked to chemical synthesis. This study explores an optimized methodology for Cer extraction. Rice bran was subjected to co-fermentation using select… read more here.

Keywords: rice bran; yeast; lipidomic profiling; cer ... See more keywords

RP-UHPLC/MS/MS Provides Enhanced Lipidomic Profiling of Human Serum in Pancreatic Cancer

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Published in 2025 at "Analytica Chimica Acta"

DOI: 10.1101/2025.09.15.25335762

Abstract: Background Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, mainly due to the late diagnosis and the lack of reliable biomarkers. Lipidomics provides a promising approach for identifying disease-related alterations, but existing… read more here.

Keywords: cancer; serum; human serum; profiling human ... See more keywords

Lipidomic profiling reveals free fatty acid alterations in plasma from patients with atrial fibrillation

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Published in 2018 at "PLoS ONE"

DOI: 10.1371/journal.pone.0196709

Abstract: Atrial fibrillation (AF) is the most common cardiac arrhythmia, and its incidence is increasing worldwide. One method used to restore sinus rhythm is direct current cardioversion (DCCV). Despite the high success rate of DCCV, AF… read more here.

Keywords: atrial fibrillation; fatty acid; free fatty; plasma patients ... See more keywords
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Metabolomic/lipidomic profiling of COVID-19 and individual response to tocilizumab.

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Published in 2021 at "PLoS pathogens"

DOI: 10.1371/journal.ppat.1009243

Abstract: The current pandemic emergence of novel coronavirus disease (COVID-19) poses a relevant threat to global health. SARS-CoV-2 infection is characterized by a wide range of clinical manifestations, ranging from absence of symptoms to severe forms… read more here.

Keywords: response; metabolomic lipidomic; lipidomic profiling; sars cov ... See more keywords