Mass spectrometry‐based proteomic analysis reveals the interacting partners of lipin1
Sign Up to like & getrecommendations! Published in 2018 at "IUBMB Life"
DOI: 10.1002/iub.1873
Abstract: As a lipin family founding member, lipin1 exerts dual functions as a phosphatidate phosphatase enzyme and/or a co‐transcriptional regulator in lipid metabolism. In fact, it is also involved in many other cell processes. In this… read more here.
Keywords: lipin1; mass; mass spectrometry; proteomic analysis ... See more keywords
Lipin1 Alleviates Autophagy Disorder in Sciatic Nerve and Improves Diabetic Peripheral Neuropathy.
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DOI: 10.1007/s12035-021-02540-5
Abstract: Diabetic peripheral neuropathy (DPN) is a chronic complication of diabetes, and its neural mechanisms underlying the pathogenesis remain unclear. Autophagy plays an important role in neurodegenerative diseases and nerve tissue injury. Lipin1 is a phosphatidic… read more here.
Keywords: lipin1; peripheral neuropathy; dpn; sciatic nerve ... See more keywords
NAT10-mediated ac4C modification of Lipin1 mRNA contributes to the pathogenesis of PWMI
Sign Up to like & getrecommendations! Published in 2025 at "JCI Insight"
DOI: 10.1172/jci.insight.193712
Abstract: Preterm white matter injury (PWMI) is a leading cause of cerebral palsy and chronic neurological disabilities in premature infants. It is characterized by defects in oligodendrocyte precursor cell (OPC) differentiation and dysmyelination. Currently, there are… read more here.
Keywords: lipin1; pwmi; lipin1 mrna; ac4c modification ... See more keywords