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   Articles with "lipl32" as a keyword



Development and validation of a modified TaqMan based real-time PCR assay targeting the lipl32 gene for detection of pathogenic Leptospira in canine urine samples

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recommendations! Published in 2018 at "Brazilian Journal of Microbiology"

DOI: 10.1016/j.bjm.2017.09.004

Abstract: A modified TaqMan real-time polymerase chain reaction targeting a 138 bp fragment within the lipl32 gene was developed to identify exclusively pathogenic Leptospira spp. in dog urine samples. Thirty-five samples from dogs with suspected clinical… read more here.

Keywords: modified taqman; real time; pathogenic leptospira; gene ... See more keywords

Assessment of the immunogenicity of the leptospiral LipL32, LigAni, and LigBrep recombinant proteins in the sheep model.

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recommendations! Published in 2019 at "Comparative immunology, microbiology and infectious diseases"

DOI: 10.1016/j.cimid.2019.05.012

Abstract: Veterinary leptospirosis vaccines are composed of bacterins and present limitations, for example, the need for bacteriological culture and serovar-dependent immunity. Recombinant antigens represent a promising alternative. LigAni, LigBrep, and LipL32 proteins have been shown to… read more here.

Keywords: lipl32; recombinant proteins; ligani ligbrep; group ... See more keywords
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Leptospira collagenase and LipL32 for antibody detection in leptospirosis.

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recommendations! Published in 2021 at "Journal of immunological methods"

DOI: 10.1016/j.jim.2021.113168

Abstract: Various Leptospira components have been identified as candidate antigens for the detection of antibody to Leptospira. LipL32 is a Leptospira membrane protein which has been widely studied. The report of Leptospira whole-genome sequencing demonstrated that… read more here.

Keywords: detection; antibody detection; cola protein; cola ... See more keywords

Design, Development and Immunogenic Evaluation of a Novel Lipl32 Recombinant Protein of Local Pathogenic Leptospira Serovars.

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recommendations! Published in 2024 at "Archives of Razi Institute"

DOI: 10.32592/ari.2025.80.1.103

Abstract: Leptospirosis, a significant yet often overlooked zoonotic disease, is distributed worldwide, particularly in tropical and subtropical regions. The manifestation of its symptoms can be deceptive, often leading to misdiagnosis due to its resemblance to other… read more here.

Keywords: development; pathogenic leptospira; lipl32; rlipl32 protein ... See more keywords

Evaluation of LipL32 and LigA/LigB Knockdown Mutants in Leptospira interrogans Serovar Copenhageni: Impacts to Proteome and Virulence

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recommendations! Published in 2022 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2021.799012

Abstract: Leptospirosis is a worldwide zoonosis caused by pathogenic species of the genus Leptospira. The recent application of CRISPR interference (CRISPRi) to Leptospira facilitates targeted gene silencing and provides a new tool to investigate pathogenic mechanisms… read more here.

Keywords: comparison control; lipl32; liga ligb; virulence ... See more keywords