Detection of mycobacterial lipoarabinomannan in serum for diagnosis of active tuberculosis.
Sign Up to like & getrecommendations! Published in 2019 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2019.114937
Abstract: Urinary detection of Mycobacterium tuberculosis lipoarabinomannan (LAM) for tuberculosis (TB) diagnosis is well characterized, but the utility of serum LAM detection remains unclear. We developed an assay for serum LAM detection using single-molecule array (Simoa),… read more here.
Keywords: lipoarabinomannan; detection; diagnosis; tuberculosis ... See more keywords
Biosynthesis of the Methylthioxylose Capping Motif of Lipoarabinomannan in Mycobacterium tuberculosis.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical biology"
DOI: 10.1021/acschembio.6b01071
Abstract: Lipoarabinomannan (LAM) is a lipoglycan found in abundant quantities in the cell envelope of all mycobacteria. The nonreducing arabinan termini of LAM display species-specific structural microheterogeneity that impacts the biological activity of the entire molecule.… read more here.
Keywords: lipoarabinomannan; biosynthesis; capping motif; tuberculosis ... See more keywords
Biomarkers for tuberculosis: the case for lipoarabinomannan
Sign Up to like & getrecommendations! Published in 2019 at "ERJ Open Research"
DOI: 10.1183/23120541.00115-2018
Abstract: Tuberculosis (TB) is considered the most onerous of infectious diseases according to recent reports from the World Health Organization. Available tests for TB diagnosis present severe limitations, and a reliable point-of-care (POC) diagnostic test does… read more here.
Keywords: lipoarabinomannan; lam; biomarkers tuberculosis; test ... See more keywords