Sputum lipoarabinomannan (LAM) as a biomarker to determine sputum mycobacterial load: exploratory and model-based analyses of integrated data from four cohorts
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DOI: 10.1186/s12879-022-07308-3
Abstract: Background Despite the high global disease burden of tuberculosis (TB), the disease caused by Mycobacterium tuberculosis ( Mtb ) infection, novel treatments remain an urgent medical need. Development efforts continue to be hampered by the reliance… read more here.
Keywords: biomarker; sputum lipoarabinomannan; lam; treatment ... See more keywords
Sensitive electrochemiluminescence (ECL) immunoassays for detecting lipoarabinomannan (LAM) and ESAT-6 in urine and serum from tuberculosis patients
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DOI: 10.1371/journal.pone.0215443
Abstract: Background Tuberculosis (TB) infection was responsible for an estimated 1.3 million deaths in 2017. Better diagnostic tools are urgently needed. We sought to determine whether accurate TB antigen detection in blood or urine has the… read more here.
Keywords: ecl immunoassays; urine serum; lam esat; lipoarabinomannan lam ... See more keywords
Potential value of urine lateral-flow lipoarabinomannan (LAM) test for diagnosing tuberculosis among severely acute malnourished children
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DOI: 10.1371/journal.pone.0250933
Abstract: Background Tuberculosis (TB) is a serious co-morbidity among children with severe acute malnutrition (SAM) and TB diagnosis remains particularly challenging in the very young. We explored whether, in a low HIV-prevalence setting, the detection of… read more here.
Keywords: group; tuberculosis; lipoarabinomannan lam; test ... See more keywords