The anti-bacterial iron-restriction defence mechanisms of egg white; the potential role of three lipocalin-like proteins in resistance against Salmonella
Sign Up to like & getrecommendations! Published in 2019 at "Biometals"
DOI: 10.1007/s10534-019-00180-w
Abstract: Salmonella enterica serovar Enteritidis (SE) is the most frequently-detected Salmonella in foodborne outbreaks in the European Union. Among such outbreaks, egg and egg products were identified as the most common vehicles of infection. Possibly, the… read more here.
Keywords: salmonella; lipocalin; iron; egg white ... See more keywords
Paradoxical role of lipocalin-2 in metabolic disorders and neurological complications.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2019.113626
Abstract: Lipocalin-2 (LCN2), also known as 24p3 and neutrophil gelatinase-associated lipocalin (NGAL), is a 25-kDa secreted protein implicated in various metabolic and inflammatory diseases.Early studies suggest the protective function of LCN2 in which it acts as… read more here.
Keywords: lcn2; neurological complications; lipocalin; metabolic disorders ... See more keywords
CSIG-20. LIPOCALIN-2 DRIVES CELL-INTRINSIC FUNCTIONS IN GLIOBLASTOMA
Sign Up to like & getrecommendations! Published in 2024 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noae165.0269
Abstract: Glioblastoma (GBM) continues to persist despite aggressive therapies, many of which are cytotoxic, and therapeutic failure is driven, in part, by the tumor cell’s ability to evade multiple forms of cell death, including ferroptosis. Lipocalin-2… read more here.
Keywords: tumor cell; iron; lcn2 knockdown; cell ... See more keywords
The Plastid Lipocalin LCNP Is Required for Sustained Photoprotective Energy Dissipation in Arabidopsis[OPEN]
Sign Up to like & getrecommendations! Published in 2017 at "Plant Cell"
DOI: 10.1105/tpc.17.00536
Abstract: The sustained photoprotective mechanism negatively regulated by SUPPRESSOR OF QUENCHING1 requires the plastid lipocalin and occurs in the peripheral antenna of photosystem II under stress conditions. Light utilization is finely tuned in photosynthetic organisms to… read more here.
Keywords: lcnp required; lipocalin lcnp; lipocalin; sustained photoprotective ... See more keywords
Association of epstein barr virus, cytomegalovirus and lipocalin with periodontitis in type 2 diabetic subjects.
Sign Up to like & getrecommendations! Published in 2021 at "Oral diseases"
DOI: 10.1111/odi.14091
Abstract: OBJECTIVE The current study aims to evaluate and compare the lipocalin, adiponectin and periodontal viruses in the generalized periodontitis patients with and without diabetes mellitus. MATERIALS AND METHODS Seventy subjects were grouped into 35 systemically… read more here.
Keywords: association epstein; epstein barr; lipocalin; ebv cmv ... See more keywords
Proteasome inhibition suppresses the induction of lipocalin-2 upon systemic lipopolysaccharide challenge in mice
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Brain"
DOI: 10.1186/s13041-024-01147-w
Abstract: Lipocalin-2 (Lcn2), a protein secreted by immune-activated cells, including reactive astrocytes, is detrimental to the brain and induces neurodegeneration. We previously showed that Lcn2 levels are reduced in primary mouse astrocytes after treatment with the… read more here.
Keywords: mice; brain; lcn2 levels; challenge ... See more keywords
Lipocalin 2 Participates in the Epidermal Differentiation and Inflammatory Processes of Psoriasis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s358492
Abstract: Abstract As a multifunctional cytokine, lipocalin 2 is weakly expressed in skin and serum under normal conditions. However, it is over-expressed by neutrophils and keratinocytes in the skin lesions and sera in several skin diseases.… read more here.
Keywords: epidermal differentiation; lipocalin participates; differentiation inflammatory; participates epidermal ... See more keywords
Lipocalin-2 is associated with FGF23 in WNT1 and PLS3 osteoporosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.954730
Abstract: Background The pathogenic mechanisms of early-onset osteoporosis caused by WNT1 and PLS3 mutations are incompletely understood and diagnostic biomarkers of these disorders are limited. Recently, lipocalin-2 has been recognized as an osteokine involved in bone… read more here.
Keywords: lipocalin; wnt1 pls3; pls3 osteoporosis; pls3 ... See more keywords
Lipocalin-2 and neutrophil activation in pancreatic cancer cachexia
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1159411
Abstract: Background Cancer cachexia is a multifactorial syndrome characterized by body weight loss and systemic inflammation. The characterization of the inflammatory response in patients with cachexia is still limited. Lipocalin-2, a protein abundant in neutrophils, has… read more here.
Keywords: lipocalin; cancer cachexia; lipocalin levels; neutrophil activation ... See more keywords
Neuroinflammation Induced by Transgenic Expression of Lipocalin-2 in Astrocytes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.839118
Abstract: Transgenic mice are a useful tool for exploring various aspects of gene function. A key element of this approach is the targeted overexpression of specific genes in cells or tissues. Herein, we report for the… read more here.
Keywords: expression; neuroinflammation; lipocalin; mice ... See more keywords
N-Glycosylation of Lipocalin 2 Is Not Required for Secretion or Exosome Targeting
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.00426
Abstract: Lipocalin 2 (LCN2) is a highly conserved secreted adipokine acting as a serum transport protein for small hydrophobic molecules such as fatty acids and steroids. In addition, LCN2 limits bacterial growth by sequestering iron-containing siderophores… read more here.
Keywords: secretion exosome; secretion; lipocalin; glycosylation ... See more keywords