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   Articles with "lipogenesis" as a keyword



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Epstein–Barr Virus‐Encoded MicroRNA‐BART18‐3p Promotes Colorectal Cancer Progression by Targeting De Novo Lipogenesis

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recommendations! Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202202116

Abstract: The Epstein–Barr virus (EBV) genome encodes a cluster of 22 viral microRNAs, called miR‐BamHI‐A rightward transcripts (miR‐BARTs), which are shown to promote the development of cancer. Here, this study reports that EBV‐miR‐BART18‐3p is highly expressed… read more here.

Keywords: ebv mir; epstein barr; mir bart18; lipogenesis ... See more keywords
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Inhibition of Long Noncoding RNA Linc‐Pint by Hepatitis C Virus in Infected Hepatocytes Enhances Lipogenesis

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recommendations! Published in 2020 at "Hepatology"

DOI: 10.1002/hep.31656

Abstract: HCV often causes chronic infection in liver, cirrhosis, and, in some instances, HCC. HCV encodes several factors' those impair host genes for establishment of chronic infection. The long noncoding RNAs (lncRNAs) display diverse effects on… read more here.

Keywords: long noncoding; linc pint; lipogenesis; inhibition long ... See more keywords
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Acyl‐CoA synthetase short‐chain family member 2 (ACSS2) is regulated by SREBP‐1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells

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recommendations! Published in 2018 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.25954

Abstract: Sterol regulatory element binding protein 1 (SREBP‐1) is well‐known as the master regulator of lipogenesis in rodents. Acyl‐CoA synthetase short‐chain family member 2 (ACSS2) plays a key role in lipogenesis by synthesizing acetyl‐CoA from acetate… read more here.

Keywords: fatty acid; lipogenesis; acyl coa; acss2 ... See more keywords
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Serum lipid analysis and isotopic enrichment is suggestive of greater lipogenesis in young long-term cannabis users: A secondary analysis of a case-control study.

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recommendations! Published in 2022 at "Lipids"

DOI: 10.1002/lipd.12336

Abstract: Cannabis is now legal in many countries and while numerous studies have reported on its impact on cognition and appetite regulation, none have examined fatty acid metabolism in young cannabis users. We conducted an exploratory… read more here.

Keywords: cannabis; analysis; palmitic acid; lipogenesis ... See more keywords
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Long noncoding RNA lncARSR promotes hepatic lipogenesis via Akt/SREBP-1c pathway and contributes to the pathogenesis of nonalcoholic steatohepatitis.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.03.127

Abstract: Non-alcoholic fatty liver disease and steatohepatitis (NAFLD and NASH) account for the majority of liver disease in industrialized countries. However, the pathogenesis still unclear. Long non-coding RNAs (lncRNAs) has been reported to be involved in… read more here.

Keywords: long noncoding; lipogenesis; lncarsr; steatohepatitis ... See more keywords
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Alliin attenuates 1, 3‐dichloro‐2‐propanol‐induced lipogenesis in HepG2 cells through activation of the AMP‐activated protein kinase‐dependent pathway

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recommendations! Published in 2018 at "Life Sciences"

DOI: 10.1016/j.lfs.2017.12.040

Abstract: &NA; Accumulating evidence reveals the association of 1, 3‐dichloro‐2‐propanol (1, 3‐DCP) exposure and lipogenesis. Alliin, the most abundant sulphur compound in garlic, has been demonstrated to exhibit hypoglycemic, antioxidant and anti‐inflammatory activities. Here, we showed… read more here.

Keywords: lipogenesis; hepg2 cells; dichloro propanol; activation ... See more keywords
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FNDC4, a novel adipokine that reduces lipogenesis and promotes fat browning in human visceral adipocytes.

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recommendations! Published in 2020 at "Metabolism: clinical and experimental"

DOI: 10.1016/j.metabol.2020.154261

Abstract: BACKGROUND Fibronectin type III domain-containing protein 4 (FNDC4) constitutes a secreted factor showing a high homology in the fibronectin type III and transmembrane domains with the exercise-associated myokine irisin (FNDC5). We sought to evaluate whether… read more here.

Keywords: fndc4; lipogenesis; human visceral; novel adipokine ... See more keywords
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Adipose-Specific Knockout of Protein Kinase D1 Suppresses de novo Lipogenesis in Mice via SREBP1c-dependent Signaling.

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recommendations! Published in 2021 at "Experimental cell research"

DOI: 10.1016/j.yexcr.2021.112548

Abstract: Having healthy adipose tissue is essential for metabolic health, as excessive adipose tissue in the body can cause its dysregulation and driving chronic metabolic diseases. Protein kinase D1 (PKD1) is considered to be a key… read more here.

Keywords: pkd1; novo lipogenesis; lipogenesis; adipose tissue ... See more keywords
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miR-143-Mediated Responses to Betaine Supplement Repress Lipogenesis and Hepatic Gluconeogenesis by Targeting MAT1a and MAPK11.

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recommendations! Published in 2022 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c02940

Abstract: The liver as the central organ is responsible for lipogenesis, gluconeogenesis and one-carbon metabolism. Methyl donors (e.g., betaine) modulate metabolic homeostasis and gene regulation through one-carbon metabolism. MiR-143 regulates DNA methylation by targeting DNMT3A, thereby… read more here.

Keywords: metabolism; mir 143; gluconeogenesis; lipogenesis ... See more keywords
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AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models

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recommendations! Published in 2020 at "Acta Pharmacologica Sinica"

DOI: 10.1038/s41401-020-0472-9

Abstract: Dyslipidemia is a chronic metabolic disease characterized by elevated levels of lipids in plasma. Recently, various studies demonstrate that the increased activity of adenosine 5′-monophosphate-activated protein kinase (AMPK) causes health benefits in energy regulation. Thus,… read more here.

Keywords: ampk activator; lipogenesis; activator c24; c24 ... See more keywords

Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A

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recommendations! Published in 2020 at "Nature Communications"

DOI: 10.1038/s41467-020-19803-9

Abstract: Hepatic lipogenesis is normally tightly regulated but is aberrantly elevated in obesity. Fibroblast Growth Factor-15/19 (mouse FGF15, human FGF19) are bile acid-induced late fed-state gut hormones that decrease hepatic lipid levels by unclear mechanisms. We… read more here.

Keywords: shp dnmt3a; lipogenesis; fgf15; late fed ... See more keywords