Epstein–Barr Virus‐Encoded MicroRNA‐BART18‐3p Promotes Colorectal Cancer Progression by Targeting De Novo Lipogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202202116
Abstract: The Epstein–Barr virus (EBV) genome encodes a cluster of 22 viral microRNAs, called miR‐BamHI‐A rightward transcripts (miR‐BARTs), which are shown to promote the development of cancer. Here, this study reports that EBV‐miR‐BART18‐3p is highly expressed… read more here.
Keywords: ebv mir; epstein barr; mir bart18; lipogenesis ... See more keywords
ATAD3 is a limiting factor in mitochondrial biogenesis and adipogenesis of white adipocyte‐like 3T3‐L1 cells
Sign Up to like & getrecommendations! Published in 2024 at "Cell Biology International"
DOI: 10.1002/cbin.12206
Abstract: ATAD3 is a vital ATPase of the inner mitochondrial membrane of pluri‐cellular eukaryotes, with largely unknown functions but early required for organism development as necessary for mitochondrial biogenesis. ATAD3 knock‐down in C. elegans inhibits at… read more here.
Keywords: biogenesis; adipogenesis; mitochondrial biogenesis; atad3 ... See more keywords
Inhibition of Long Noncoding RNA Linc‐Pint by Hepatitis C Virus in Infected Hepatocytes Enhances Lipogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31656
Abstract: HCV often causes chronic infection in liver, cirrhosis, and, in some instances, HCC. HCV encodes several factors' those impair host genes for establishment of chronic infection. The long noncoding RNAs (lncRNAs) display diverse effects on… read more here.
Keywords: long noncoding; linc pint; lipogenesis; inhibition long ... See more keywords
Acyl‐CoA synthetase short‐chain family member 2 (ACSS2) is regulated by SREBP‐1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25954
Abstract: Sterol regulatory element binding protein 1 (SREBP‐1) is well‐known as the master regulator of lipogenesis in rodents. Acyl‐CoA synthetase short‐chain family member 2 (ACSS2) plays a key role in lipogenesis by synthesizing acetyl‐CoA from acetate… read more here.
Keywords: fatty acid; lipogenesis; acyl coa; acss2 ... See more keywords
Serum lipid analysis and isotopic enrichment is suggestive of greater lipogenesis in young long-term cannabis users: A secondary analysis of a case-control study.
Sign Up to like & getrecommendations! Published in 2022 at "Lipids"
DOI: 10.1002/lipd.12336
Abstract: Cannabis is now legal in many countries and while numerous studies have reported on its impact on cognition and appetite regulation, none have examined fatty acid metabolism in young cannabis users. We conducted an exploratory… read more here.
Keywords: cannabis; analysis; palmitic acid; lipogenesis ... See more keywords
Long noncoding RNA lncARSR promotes hepatic lipogenesis via Akt/SREBP-1c pathway and contributes to the pathogenesis of nonalcoholic steatohepatitis.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.03.127
Abstract: Non-alcoholic fatty liver disease and steatohepatitis (NAFLD and NASH) account for the majority of liver disease in industrialized countries. However, the pathogenesis still unclear. Long non-coding RNAs (lncRNAs) has been reported to be involved in… read more here.
Keywords: long noncoding; lipogenesis; lncarsr; steatohepatitis ... See more keywords
Alliin attenuates 1, 3‐dichloro‐2‐propanol‐induced lipogenesis in HepG2 cells through activation of the AMP‐activated protein kinase‐dependent pathway
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.12.040
Abstract: &NA; Accumulating evidence reveals the association of 1, 3‐dichloro‐2‐propanol (1, 3‐DCP) exposure and lipogenesis. Alliin, the most abundant sulphur compound in garlic, has been demonstrated to exhibit hypoglycemic, antioxidant and anti‐inflammatory activities. Here, we showed… read more here.
Keywords: lipogenesis; hepg2 cells; dichloro propanol; activation ... See more keywords
FNDC4, a novel adipokine that reduces lipogenesis and promotes fat browning in human visceral adipocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2020.154261
Abstract: BACKGROUND Fibronectin type III domain-containing protein 4 (FNDC4) constitutes a secreted factor showing a high homology in the fibronectin type III and transmembrane domains with the exercise-associated myokine irisin (FNDC5). We sought to evaluate whether… read more here.
Keywords: fndc4; lipogenesis; human visceral; novel adipokine ... See more keywords
Adipose-Specific Knockout of Protein Kinase D1 Suppresses de novo Lipogenesis in Mice via SREBP1c-dependent Signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2021.112548
Abstract: Having healthy adipose tissue is essential for metabolic health, as excessive adipose tissue in the body can cause its dysregulation and driving chronic metabolic diseases. Protein kinase D1 (PKD1) is considered to be a key… read more here.
Keywords: pkd1; novo lipogenesis; lipogenesis; adipose tissue ... See more keywords
miR-143-Mediated Responses to Betaine Supplement Repress Lipogenesis and Hepatic Gluconeogenesis by Targeting MAT1a and MAPK11.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c02940
Abstract: The liver as the central organ is responsible for lipogenesis, gluconeogenesis and one-carbon metabolism. Methyl donors (e.g., betaine) modulate metabolic homeostasis and gene regulation through one-carbon metabolism. MiR-143 regulates DNA methylation by targeting DNMT3A, thereby… read more here.
Keywords: metabolism; mir 143; gluconeogenesis; lipogenesis ... See more keywords
AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models
Sign Up to like & getrecommendations! Published in 2020 at "Acta Pharmacologica Sinica"
DOI: 10.1038/s41401-020-0472-9
Abstract: Dyslipidemia is a chronic metabolic disease characterized by elevated levels of lipids in plasma. Recently, various studies demonstrate that the increased activity of adenosine 5′-monophosphate-activated protein kinase (AMPK) causes health benefits in energy regulation. Thus,… read more here.
Keywords: ampk activator; lipogenesis; activator c24; c24 ... See more keywords