Articles with "lipogenic transcription" as a keyword



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Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity

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Published in 2017 at "Journal of Clinical Investigation"

DOI: 10.1172/jci89934

Abstract: Epidemiologic and animal studies implicate overconsumption of fructose in the development of nonalcoholic fatty liver disease, but the molecular mechanisms underlying fructose-induced chronic liver diseases remain largely unknown. Here, we have presented evidence supporting the… read more here.

Keywords: lipogenic transcription; fructose induced; transcription factor; chrebp ... See more keywords