Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes.
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DOI: 10.1021/jacs.1c10836
Abstract: Chronically elevated circulating fatty acid levels promote lipid accumulation in nonadipose tissues and cause lipotoxicity. Adipose triglyceride lipase (ATGL) critically determines the release of fatty acids from white adipose tissue, and accumulating evidence suggests that… read more here.
Keywords: small molecule; human adipocytes; inhibitor; lipolysis human ... See more keywords