Articles with "lipophilic efficient" as a keyword



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Lipophilic efficient phenylthiazoles with potent undecaprenyl pyrophosphatase inhibitory activity.

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Published in 2019 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2019.04.063

Abstract: Antibiotic resistance remains a pressing medical challenge for which novel antibacterial agents are urgently needed. The phenylthiazole scaffold represents a promising platform to develop novel antibacterial agents for drug-resistant infections. However, enhancing the physicochemical profile… read more here.

Keywords: novel antibacterial; lipophilic efficient; antibacterial agents; undecaprenyl pyrophosphatase ... See more keywords