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Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22628
Abstract: Lp‐PLA2 is a novel inflammation marker in cardiovascular disease. While several manufactures have registered Lp‐PLA2 activity reagents, few studies have investigated the consistency among these assays. In this study, we compared and recalibrated Lp‐PLA2 activity…
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Keywords:
associated phospholipase;
measuring lipoprotein;
phospholipase activity;
activity china ... See more keywords
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Published in 2018 at "American Heart Journal"
DOI: 10.1016/j.ahj.2017.11.010
Abstract: Background Multiple prospective studies have established an association between inflammation and higher risk of atrial fibrillation (AF), but the association between lipoprotein‐associated phospholipase A2 (Lp‐PLA2) mass and activity and incident AF has not been extensively…
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Keywords:
atrial fibrillation;
risk;
association lipoprotein;
incident ... See more keywords
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Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.10.068
Abstract: Protein tyrosine nitration (PTN) is a post translational event which results in the generation of 3-Nitrotyrosine (3-NT). High levels of 3-NT were reported in several human diseases such as Parkinson's disease, Alzheimer's disease, amylotrophic lateral…
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Keywords:
lipoprotein associated;
tyr307 tyr335;
tyrosine nitration;
associated phospholipase ... See more keywords
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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2102953118
Abstract: Significance Lp-PLA2 is a physiologically important human enzyme and an inflammatory biomarker for assessing risk factors associated with cardiovascular diseases. It is associated with low- and high-density lipoproteins in human plasma and acts on the…
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Keywords:
pla2;
allosteric regulation;
enzyme;
specificity ... See more keywords
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Published in 2022 at "Journal of thrombosis and thrombolysis"
DOI: 10.1093/eurheartjsupp/suac121.114
Abstract: The precise role of Lipoprotein associated phospholipase A2 (Lp-PlA2) in the pathogenesis of acute coronary syndromes (ACS) and in the prediction of future cardiovascular events is still debated. So far, few data exist on the…
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Keywords:
acs patients;
stemi;
nste acs;
acs ... See more keywords
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Published in 2023 at "Laboratory medicine"
DOI: 10.1093/labmed/lmac162
Abstract: OBJECTIVE Reduced left ventricular ejection fraction (LVEF) is common in hemodialysis (HD) patients. Lipoprotein-associated phospholipase A2 (Lp-PLA2) is considered an important determinant of cardiovascular events. The aim of the study was to evaluate the relationship…
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Keywords:
lvef;
ejection fraction;
reduced left;
lipoprotein associated ... See more keywords
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Published in 2019 at "Diabetic Medicine"
DOI: 10.1111/dme.14086
Abstract: To assess the relevance of lipoprotein‐associated phospholipase A2 activity as a diagnostic and prognostic marker for renal microvascular diseases.
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Keywords:
lipoprotein associated;
marker renal;
associated phospholipase;
evaluation lipoprotein ... See more keywords
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Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.747120
Abstract: Background: High lipoprotein(a) is associated with poor prognosis in patients at high risk for cardiovascular disease. Renal function based on the estimated glomerular filtration rate (eGFR) is a potential risk factor for the change of…
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Keywords:
risk;
study;
lipoprotein associated;
mortality ... See more keywords
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Published in 2018 at "Acta Cardiologica Sinica"
DOI: 10.6515/acs.201805_34(3).20170227a
Abstract: Background Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a potential therapeutic target in acute coronary syndromes. Although recent evidence does not support the routine use of manual thrombus aspiration (TA) in patients with ST-elevation myocardial infarction (STEMI)…
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Keywords:
myocardial infarction;
group;
ppci;
lipoprotein associated ... See more keywords