Frequent LPA KIV-2 Variants Lower Lipoprotein(a) Concentrations and Protect Against Coronary Artery Disease.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2021.05.037
Abstract: BACKGROUND Lipoprotein(a) (Lp(a)) concentrations are a major independent risk factor for coronary artery disease (CAD) and are mainly determined by variation in LPA. Up to 70% of the LPA coding sequence is located in the… read more here.
Keywords: lipoprotein concentrations; cad; disease; coronary artery ... See more keywords
Impact of ezetimibe on plasma lipoprotein(a) concentrations as monotherapy or in combination with statins: a systematic review and meta-analysis of randomized controlled trials
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-36204-7
Abstract: The aim of this meta-analysis of randomized placebo-controlled clinical trials was to assess the effect of ezetimibe on plasma lipoprotein(a) concentrations. Only randomized placebo-controlled trials investigating the impact of ezetimibe treatment on cholesterol lowering that… read more here.
Keywords: lipoprotein concentrations; analysis; impact; plasma lipoprotein ... See more keywords
Lipoprotein(a) and Cardiovascular Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical chemistry"
DOI: 10.1093/clinchem/hvaa247
Abstract: BACKGROUND High lipoprotein(a) concentrations present in 10%-20% of the population have long been linked to increased risk of ischemic cardiovascular disease. It is unclear whether high concentrations represent an unmet medical need. Lipoprotein(a) is currently… read more here.
Keywords: lipoprotein concentrations; disease; lipoprotein cardiovascular; cardiovascular disease ... See more keywords