Articles with "liposomal amphotericin" as a keyword



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Fluconazole Non-susceptible Cryptococcus neoformans, Relapsing/Refractory Cryptococcosis and Long-term Use of Liposomal Amphotericin B in an AIDS Patient

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Published in 2017 at "Mycopathologia"

DOI: 10.1007/s11046-017-0165-1

Abstract: The treatment of cryptococcosis is hampered by inefficacy or intolerance to the recommended antifungal agents. A patient diagnosed with AIDS had multiple relapses of cryptococcal infection, which became refractory to antifungal agents during the course… read more here.

Keywords: cryptococcus neoformans; use; amphotericin; liposomal amphotericin ... See more keywords

Use of nebulized liposomal amphotericin B and posaconazole as antifungal prophylaxis in patients with severe SARS-CoV2 infection in intensive care unit

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Published in 2024 at "Infection"

DOI: 10.1007/s15010-024-02234-9

Abstract: COVID-19 associated pulmonary aspergillosis (CAPA) is common and linked with high fatality rates. To assess the impact on the incidence and outcome of CAPA of an antifungal prophylaxis (AFP) we compared two cohorts of COVID-19… read more here.

Keywords: capa; intensive care; antifungal prophylaxis; nebulized liposomal ... See more keywords

Pseudohypophosphatemia associated with high-dose liposomal amphotericin B therapy.

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Published in 2017 at "Clinical biochemistry"

DOI: 10.1016/j.clinbiochem.2017.05.016

Abstract: BACKGROUND Hypophosphatemia is commonly observed in critically ill patients. Inorganic phosphorus is quantified by spectrophotometric measurement of a phosphomolybdate complex, a method with multiple documented interferents. Our clinical laboratory was contacted to investigate a case… read more here.

Keywords: high dose; liposomal amphotericin; dose liposomal; amphotericin therapy ... See more keywords

Bioanalysis of free and liposomal Amphotericin B in rat plasma using solid phase extraction and protein precipitation followed by LC‐MS/MS

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Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"

DOI: 10.1016/j.jpba.2018.06.014

Abstract: HIGHLIGHTSFree and liposomal Amphotericin B were effectively separated in rat plasma by solid phase extraction without liposomal breakdown.Liposomal Amphotericin B was quantified by calculating the difference between total and free Amphotericin B.The method was successfully… read more here.

Keywords: rat plasma; amphotericin; phase extraction; liposomal amphotericin ... See more keywords

Successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin B after invasive pulmonary zygomycosis

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Published in 2017 at "Medical Mycology Case Reports"

DOI: 10.1016/j.mmcr.2017.07.002

Abstract: A 54-year-old woman with acute myeloid leukemia (AML) achieved complete remission by induction chemotherapy, but developed zygomycosis after consolidation therapy. As zygomycosis could not be cured by liposomal amphotericin B and micafungin, left lower lobectomy… read more here.

Keywords: zygomycosis; liposomal amphotericin; cell transplantation; administration liposomal ... See more keywords
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Treatment With Liposomal Amphotericin B for All Confirmed Cases of Human Visceral Leishmaniasis in Brazil: A Budget Impact Analysis.

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Published in 2020 at "Value in health regional issues"

DOI: 10.1016/j.vhri.2020.05.006

Abstract: OBJECTIVES To estimate the budget impact of the expansion of liposomal amphotericin B use for all confirmed cases of visceral leishmaniasis (VL) in Brazil. Currently, the first-line medicine for VL treatment is meglumine antimoniate. Liposomal… read more here.

Keywords: amphotericin; budget impact; analysis; treatment ... See more keywords

Unusual endoscopic findings in an immunosuppressed patient.

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Published in 2021 at "Endoscopy"

DOI: 10.1055/a-1328-2365

Abstract: Immunosuppressed patients are susceptible to infections by opportunistic agents such as Leishmania that could cause visceral leishmaniasis with gastrointestinal involvement in up to 10% of cases. We report a 41-year-old man with human immunodeficiency virus… read more here.

Keywords: immunosuppressed patient; endoscopic findings; findings immunosuppressed; liposomal amphotericin ... See more keywords

The care and feeding of a commercial liposomal product: liposomal amphotericin B (AmBisome®)

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Published in 2017 at "Journal of Liposome Research"

DOI: 10.1080/08982104.2017.1380664

Abstract: Abstract AmBisome (liposomal amphotericin B) is among the earliest approved liposomal therapeutics, and has been in commercial use since the early 1990s. This review provides examples of non-clinical, regulatory, clinical label expansion, adverse event management,… read more here.

Keywords: liposomal product; liposomal amphotericin; product; commercial liposomal ... See more keywords

Dr. Edward Krusen and his contributions to polio patients

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Published in 2022 at "Baylor University Medical Center Proceedings"

DOI: 10.1080/08998280.2022.2045170

Abstract: ANTIFUNGAL COMBINATIONS IN MUCORMYCOSIS Brigmon and colleagues reported the safety of long-term isavuconazole in a poorly controlled diabetic with rhinocerebral mucormycosis. The authors diagnosed rhino-orbital mucormycosis and managed it with several antifungals, including liposomal amphotericin-B,… read more here.

Keywords: krusen contributions; liposomal amphotericin; polio patients; mucormycosis ... See more keywords

Economic impact of managing invasive mold disease with isavuconazole compared with liposomal amphotericin B followed by posaconazole in Spain

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Published in 2024 at "Expert Review of Anti-infective Therapy"

DOI: 10.1080/14787210.2024.2327517

Abstract: ABSTRACT Background Invasive fungal infections (IFI) are associated with significant morbidity and mortality. The objective of this work was to compare the costs per adult patient, associated with intravenous isavuconazole (ISAV) followed by oral ISAV… read more here.

Keywords: treatment; amb posa; isav; amphotericin followed ... See more keywords

Preclinical Studies of the Nebulized Delivery of Liposomal Amphotericin B.

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Published in 2022 at "Journal of aerosol medicine and pulmonary drug delivery"

DOI: 10.1089/jamp.2022.0003

Abstract: Background: Intravenous liposomal amphotericin B (L-AMB) has accompanying side effects that may be diminished when administering an inhaled form. Delivery systems for inhaled or aerosolized L-AMB vary, and there has not been a recent comparison… read more here.

Keywords: liposomal amphotericin; amb; studies nebulized; delivery ... See more keywords