Fluconazole Non-susceptible Cryptococcus neoformans, Relapsing/Refractory Cryptococcosis and Long-term Use of Liposomal Amphotericin B in an AIDS Patient
Sign Up to like & getrecommendations! Published in 2017 at "Mycopathologia"
DOI: 10.1007/s11046-017-0165-1
Abstract: The treatment of cryptococcosis is hampered by inefficacy or intolerance to the recommended antifungal agents. A patient diagnosed with AIDS had multiple relapses of cryptococcal infection, which became refractory to antifungal agents during the course… read more here.
Keywords: cryptococcus neoformans; use; amphotericin; liposomal amphotericin ... See more keywords
Pseudohypophosphatemia associated with high-dose liposomal amphotericin B therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2017.05.016
Abstract: BACKGROUND Hypophosphatemia is commonly observed in critically ill patients. Inorganic phosphorus is quantified by spectrophotometric measurement of a phosphomolybdate complex, a method with multiple documented interferents. Our clinical laboratory was contacted to investigate a case… read more here.
Keywords: high dose; liposomal amphotericin; dose liposomal; amphotericin therapy ... See more keywords
Bioanalysis of free and liposomal Amphotericin B in rat plasma using solid phase extraction and protein precipitation followed by LC‐MS/MS
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.06.014
Abstract: HIGHLIGHTSFree and liposomal Amphotericin B were effectively separated in rat plasma by solid phase extraction without liposomal breakdown.Liposomal Amphotericin B was quantified by calculating the difference between total and free Amphotericin B.The method was successfully… read more here.
Keywords: rat plasma; amphotericin; phase extraction; liposomal amphotericin ... See more keywords
Successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin B after invasive pulmonary zygomycosis
Sign Up to like & getrecommendations! Published in 2017 at "Medical Mycology Case Reports"
DOI: 10.1016/j.mmcr.2017.07.002
Abstract: A 54-year-old woman with acute myeloid leukemia (AML) achieved complete remission by induction chemotherapy, but developed zygomycosis after consolidation therapy. As zygomycosis could not be cured by liposomal amphotericin B and micafungin, left lower lobectomy… read more here.
Keywords: zygomycosis; liposomal amphotericin; cell transplantation; administration liposomal ... See more keywords
Treatment With Liposomal Amphotericin B for All Confirmed Cases of Human Visceral Leishmaniasis in Brazil: A Budget Impact Analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Value in health regional issues"
DOI: 10.1016/j.vhri.2020.05.006
Abstract: OBJECTIVES To estimate the budget impact of the expansion of liposomal amphotericin B use for all confirmed cases of visceral leishmaniasis (VL) in Brazil. Currently, the first-line medicine for VL treatment is meglumine antimoniate. Liposomal… read more here.
Keywords: amphotericin; budget impact; analysis; treatment ... See more keywords
Unusual endoscopic findings in an immunosuppressed patient.
Sign Up to like & getrecommendations! Published in 2021 at "Endoscopy"
DOI: 10.1055/a-1328-2365
Abstract: Immunosuppressed patients are susceptible to infections by opportunistic agents such as Leishmania that could cause visceral leishmaniasis with gastrointestinal involvement in up to 10% of cases. We report a 41-year-old man with human immunodeficiency virus… read more here.
Keywords: immunosuppressed patient; endoscopic findings; findings immunosuppressed; liposomal amphotericin ... See more keywords
The care and feeding of a commercial liposomal product: liposomal amphotericin B (AmBisome®)
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Liposome Research"
DOI: 10.1080/08982104.2017.1380664
Abstract: Abstract AmBisome (liposomal amphotericin B) is among the earliest approved liposomal therapeutics, and has been in commercial use since the early 1990s. This review provides examples of non-clinical, regulatory, clinical label expansion, adverse event management,… read more here.
Keywords: liposomal product; liposomal amphotericin; product; commercial liposomal ... See more keywords
Dr. Edward Krusen and his contributions to polio patients
Sign Up to like & getrecommendations! Published in 2022 at "Baylor University Medical Center Proceedings"
DOI: 10.1080/08998280.2022.2045170
Abstract: ANTIFUNGAL COMBINATIONS IN MUCORMYCOSIS Brigmon and colleagues reported the safety of long-term isavuconazole in a poorly controlled diabetic with rhinocerebral mucormycosis. The authors diagnosed rhino-orbital mucormycosis and managed it with several antifungals, including liposomal amphotericin-B,… read more here.
Keywords: krusen contributions; liposomal amphotericin; polio patients; mucormycosis ... See more keywords
Preclinical Studies of the Nebulized Delivery of Liposomal Amphotericin B.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of aerosol medicine and pulmonary drug delivery"
DOI: 10.1089/jamp.2022.0003
Abstract: Background: Intravenous liposomal amphotericin B (L-AMB) has accompanying side effects that may be diminished when administering an inhaled form. Delivery systems for inhaled or aerosolized L-AMB vary, and there has not been a recent comparison… read more here.
Keywords: liposomal amphotericin; amb; studies nebulized; delivery ... See more keywords
Liposomal amphotericin B—the present
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkac352
Abstract: Abstract Most invasive fungal infections are opportunistic in nature but the epidemiology is constantly changing, with new risk groups being identified. Neutropenia is a classical risk factor for fungal infections, while critically ill patients in… read more here.
Keywords: liposomal amphotericin; first line; risk; fungal infections ... See more keywords
Population pharmacokinetics of liposomal amphotericin B in adults with HIV-associated cryptococcal meningoencephalitis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkac389
Abstract: Abstract Background Single, high-dose liposomal amphotericin B (LAmB; AmBisome, Gilead Sciences) has demonstrated non-inferiority to amphotericin B deoxycholate in combination with other antifungals for averting all-cause mortality from HIV-associated cryptococcal meningitis. There are limited data… read more here.
Keywords: cryptococcal meningoencephalitis; population; analysis; liposomal amphotericin ... See more keywords