Nano-formulations for bone-specific delivery of siRNA for CrkII silencing-induced regulation of bone formation and resorption to maximize therapeutic potential for bone-related diseases.
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DOI: 10.1039/d2bm02038f
Abstract: CrkII, a member of the adaptor protein family, is known to participate in bone homeostasis via the regulation of osteoclasts and osteoblasts. Therefore, silencing CrkII would beneficially impact the bone microenvironment. In this study, CrkII… read more here.
Keywords: specific delivery; bone specific; bone; liposome sicrkii ... See more keywords