Reduction responsive liposomes based on paclitaxel-ss-lysophospholipid with high drug loading for intracellular delivery.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.04.060
Abstract: In this report, a novel redox-responsive liposomes based on disulfide derivative paclitaxel-ss-lysophosphatidylcholine prodrug (PTX-ss-PC) with high PTX loading was developed for triggering drug release. First of all, PTX-ss-PC was synthesized by a facile esterification and… read more here.
Keywords: reduction; responsive liposomes; ptx; drug ... See more keywords
Pharmaceutical Development and Design of Thermosensitive Liposomes Based on the QbD Approach
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27051536
Abstract: This study aimed to produce thermosensitive liposomes (TSL) by applying the quality by design (QbD) concept. In this paper, our research group collected and studied the parameters that significantly impact the quality of the liposomal… read more here.
Keywords: design thermosensitive; pharmaceutical development; development design; design ... See more keywords