Dual Functionalized Liposomes for Selective Delivery of Poorly Soluble Drugs to Inflamed Brain Regions
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DOI: 10.3390/pharmaceutics14112402
Abstract: Dual functionalized liposomes were developed to cross the blood–brain barrier (BBB) and to release their cargo in a pathological matrix metalloproteinase (MMP)-rich microenvironment. Liposomes were surface-functionalized with a modified peptide deriving from the receptor-binding domain… read more here.
Keywords: mmp sensitive; brain; functionalized liposomes; dual functionalized ... See more keywords