Dynamic Profiling of Lipoteichoic Acid (LTA) and/or Lipopolysaccharide (LPS) Positive Extracellular Vesicles in Plasma as Diagnostic and Prognostic Biomarkers for Bacterial Infection
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202506613
Abstract: Bacterial extracellular vesicles (EVs) are emerging as promising biomarkers for diagnosing bacterial infections. This study explores the diagnostic potential of plasma EVs carrying bacterial lipopolysaccharide (LPS) or lipoteichoic acid (LTA). Using immunoelectron microscopy (IEM) and… read more here.
Keywords: extracellular vesicles; lps positive; bacterial infection; lipopolysaccharide lps ... See more keywords
Primary versus post-treatment apical periodontitis: microbial composition, lipopolysaccharides and lipoteichoic acid levels, signs and symptoms
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Oral Investigations"
DOI: 10.1007/s00784-019-03191-6
Abstract: Objectives To compare the microbial load and composition and to determine the lipopolysaccharides (LPS) and lipoteichoic acid (LTA) concentrations found in primary apical periodontitis (PAP) and post-treatment apical periodontitis (PTAP), correlating these findings with clinical/tomographic… read more here.
Keywords: lipoteichoic acid; signs symptoms; apical periodontitis; post treatment ... See more keywords
Costunolide ameliorates lipoteichoic acid‐induced acute lung injury via attenuating MAPK signaling pathway
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.06.017
Abstract: &NA; Lipoteichoic acid (LTA)‐induced acute lung injury (ALI) is an experimental model for mimicking Gram‐positive bacteria‐induced pneumonia that is a refractory disease with lack of effective medicines. Here, we reported that costunolide, a sesquiterpene lactone,… read more here.
Keywords: lipoteichoic acid; lta induced; costunolide; signaling pathway ... See more keywords
Lipopolysaccharide and lipoteichoic acid influence milk production ability via different early responses in bovine mammary epithelial cells.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2021.112472
Abstract: Lipopolysaccharide (LPS) and lipoteichoic acid (LTA) are cell wall components of Escherichia coli and Staphylococcus aureus, which cause clinical and subclinical mastitis, respectively. However, the reason of the difference in symptoms by pathogen type remains… read more here.
Keywords: milk; lipoteichoic acid; influence; bovine mammary ... See more keywords
Structure-Based Discovery of Lipoteichoic Acid Synthase Inhibitors
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DOI: 10.1021/acs.jcim.2c00300
Abstract: Lipoteichoic acid synthase (LtaS) is a key enzyme for the cell wall biosynthesis of Gram-positive bacteria. Gram-positive bacteria that lack lipoteichoic acid (LTA) exhibit impaired cell division and growth defects. Thus, LtaS appears to be… read more here.
Keywords: structure; acid synthase; compound 1771; lipoteichoic acid ... See more keywords
Membrane vesicles of Lacticaseibacillus rhamnosus JB-1 contain immunomodulatory lipoteichoic acid and are endocytosed by intestinal epithelial cells
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-93311-8
Abstract: Intestinal bacteria have diverse and complex influence on their host. Evidence is accumulating that this may be mediated in part by bacterial extracellular membrane vesicles (MV), nanometer-sized particles important for intercellular communication. Little is known… read more here.
Keywords: lipoteichoic acid; epithelial cells; intestinal epithelial; membrane vesicles ... See more keywords
Solution and interfacial self-assembly of Bacillus subtilis bacterial lipoteichoic acid (LTA): nanoclustering, and effects of Ca2+ and temperature.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr00595f
Abstract: Lipoteichoic acid (LTA) is a major structural and functional molecule in the Gram-positive bacteria membrane. Knowledge of LTA adsorption at interfaces and its solution self-assembly is crucial to understanding its role in bacterial adhesion and… read more here.
Keywords: self assembly; microscopy; solution; lipoteichoic acid ... See more keywords
SpbR controls lipoteichoic acid length by directly inhibiting signal peptidase SpsB in Staphylococcus aureus.
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2426464122
Abstract: Significance Signal peptidases are essential for protein secretion in all bacteria. In Staphylococcus aureus, the signal peptidase SpsB also cleaves lipoteichoic acid synthase (LtaS), which assembles the essential surface polymer lipoteichoic acid (LTA). Whether cleavage… read more here.
Keywords: peptidase spsb; signal peptidase; staphylococcus aureus; spsb ... See more keywords
MCPIP1 mediates inflammatory responses induced by lipopolysaccharide and lipoteichoic acid in bovine mammary epithelial cells
Sign Up to like & getrecommendations! Published in 2019 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.1093/abbs/gmy163
Abstract: Monocyte chemoattractant protein-induced protein 1 (MCPIP1) is a kind of zinc finger RNA binding protein, which exerts immune responses in a variety of cell types. However, the role of MCPIP1 in bovine mammary epithelial cells… read more here.
Keywords: lipoteichoic acid; epithelial cells; mammary epithelial; bovine ... See more keywords
Lipoteichoic acid mediates binding of a Lactobacillus S-layer protein
Sign Up to like & getrecommendations! Published in 2018 at "Glycobiology"
DOI: 10.1093/glycob/cwx102
Abstract: Abstract The Gram-positive lactic acid bacterium Lactobacillus buchneri CD034 is covered by a two-dimensional crystalline, glycoproteinaceous cell surface (S-) layer lattice. While lactobacilli are extensively exploited as cell surface display systems for applied purposes, questions… read more here.
Keywords: lipoteichoic acid; layer; spectroscopy; cell wall ... See more keywords
Lipoteichoic acid as a Potential Noninvasive Marker of Biofilm in Dialysis Access.
Sign Up to like & getrecommendations! Published in 2019 at "ASAIO Journal"
DOI: 10.1097/mat.0000000000001091
Abstract: Tunneled central venous catheters (TCVCs) are colonized by Gram-positive organisms and form biofilm. Lipoteichoic acid (LTA) is a Gram-positive cell wall component that can be measured in serum. The purpose of this pilot study was… read more here.
Keywords: patients tcvcs; removed clinical; access; biofilm ... See more keywords