Lipotoxic Impairment of Mitochondrial Function in β-Cells: A Review
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DOI: 10.3390/antiox10020293
Abstract: Lipotoxicity is a major contributor to type 2 diabetes mainly promoting mitochondrial dysfunction. Lipotoxic stress is mediated by elevated levels of free fatty acids through various mechanisms and pathways. Impaired peroxisome proliferator-activated receptor (PPAR) signaling,… read more here.
Keywords: lipotoxic impairment; fatty acids; function cells; cellular senescence ... See more keywords