Lipoxin A4 and its analog suppress inflammation by modulating HMGB1 translocation and expression in psoriasis
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-07485-1
Abstract: Psoriasis is a chronic inflammatory skin disease that affects 2–3% of the global population, and there is still no known possibility of a cure. Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual… read more here.
Keywords: hmgb1 translocation; expression; lipoxin; psoriasis ... See more keywords
Lipoxin A4 Reduces Ventilator-Induced Lung Injury in Rats with Large-Volume Mechanical Ventilation
Sign Up to like & getrecommendations! Published in 2020 at "Mediators of Inflammation"
DOI: 10.1155/2020/6705985
Abstract: Ventilator-induced lung injury (VILI) is a severe and inevitable complication in patients who require mechanical ventilation (MV) for respiratory support. Lipoxin A4 is an endogenous anti-inflammatory and antioxidant mediator. The present study determined the effects… read more here.
Keywords: ventilator induced; induced lung; mechanical ventilation; lipoxin ... See more keywords
Could Lipoxins Represent a New Standard in Ischemic Stroke Treatment?
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22084207
Abstract: Introduction: Cardiovascular diseases including stroke are one of the most common causes of death. Their main cause is atherosclerosis and chronic inflammation in the body. An ischemic stroke may occur as a result of the… read more here.
Keywords: lipoxins represent; ischemic stroke; could lipoxins; inflammation ... See more keywords
Amnion Epithelial Cells Promote Lung Repair via Lipoxin A4
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cells Translational Medicine"
DOI: 10.5966/sctm.2016-0077
Abstract: Human amnion epithelial cells (hAECs) have been shown to possess potent immunomodulatory properties across a number of disease models. Recently, we reported that hAECs influence macrophage polarization and activity, and that this step was dependent… read more here.
Keywords: medicine; epithelial cells; amnion epithelial; macrophage ... See more keywords