Protein-Interaction Affinity Gradient Drives [4Fe–4S] Cluster Insertion in Human Lipoyl Synthase
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DOI: 10.1021/jacs.1c13626
Abstract: Human lipoyl synthase (LIAS) is an enzyme containing two [4Fe–4S] clusters (named FeSRS and FeSaux) involved in the biosynthesis of the lipoyl cofactor. The mechanism by which a [4Fe–4S] cluster is inserted into LIAS has… read more here.
Keywords: lipoyl synthase; protein interaction; human lipoyl; cluster ... See more keywords