Detecting ALK, ROS1 and RET fusions and the METΔex14 splicing variant in liquid biopsies of non-small cell lung cancer patients using RNA-based techniques.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13468
Abstract: ALK, ROS1 and RET fusions and MET∆ex14 variant associate with response to targeted therapies in non-small cell lung cancer (NSCLC). Technologies for fusion testing in tissue must be adapted to liquid biopsies, which are often… read more here.
Keywords: alk ros1; ros1 ret; met ex14; liquid biopsies ... See more keywords
Cancer Liquid Biopsy Using Integrated Microfluidic Exosome Analysis Platforms
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Journal"
DOI: 10.1002/biot.201900225
Abstract: Liquid biopsies serve as both powerful noninvasive diagnostic tools for early cancer screening and prognostic tools for monitoring cancer progression and treatment efficacy. Exosomes are promising biomarkers for liquid biopsies, since these nano‐sized extracellular vesicles… read more here.
Keywords: liquid biopsies; integrated microfluidic; liquid biopsy; cancer liquid ... See more keywords
A fluid future for liquid biopsies
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22087
Abstract: O ncologists have dreamed of them for years: noninvasive alternatives to tissue biopsies that can quickly identify tumors by the cells, DNA, or other cell components that they shed into patients’ blood. Now, several promising… read more here.
Keywords: liquid biopsies; fluid future; liquid; future liquid ... See more keywords
Application of Liquid Biopsies in Cancer Targeted Therapy
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DOI: 10.1002/cpt.764
Abstract: As a growing body of evidence demonstrates intertumoral and intratumoral heterogeneity and clonal evolution, both during carcinogenesis and also throughout treatment resulting in acquired drug resistance, the utility of blood‐based assays or “liquid biopsies” is… read more here.
Keywords: application liquid; liquid biopsies; biopsies cancer; targeted therapy ... See more keywords
Patient monitoring through liquid biopsies using circulating tumor DNA
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Cancer"
DOI: 10.1002/ijc.30759
Abstract: Tumors release components such as circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), and tumor‐derived extracellular vesicles into the circulation. Multiple studies have demonstrated that molecular information about tumors and metastases can be extracted from… read more here.
Keywords: circulating tumor; liquid biopsies; tumor dna; tumor ... See more keywords
Liquid Biopsies: New Technology and Evidence
Sign Up to like & getrecommendations! Published in 2021 at "Lung Cancer"
DOI: 10.1007/978-3-030-74028-3_3
Abstract: Liquid biopsy refers to a broad category of minimally invasive test done on blood or other fluid specimens to detect fragments of tumor-derived DNA, extracellular vesicles (EVs) and circulating tumor cells (CTCs). The most common… read more here.
Keywords: liquid biopsies; liquid; new technology; technology evidence ... See more keywords
A liquid biopsy in primary lung cancer
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DOI: 10.1007/s00595-018-1659-2
Abstract: A tissue biopsy is the “golden standard” for molecular profiling that is essential in decision-making regarding treatment for malignant tumors, including primary lung cancer. However, tumor biopsies are associated with several limitations, including invasiveness and… read more here.
Keywords: primary lung; biopsy; liquid biopsies; lung cancer ... See more keywords
Progress toward liquid biopsies in pediatric solid tumors
Sign Up to like & getrecommendations! Published in 2019 at "Cancer and Metastasis Reviews"
DOI: 10.1007/s10555-019-09825-1
Abstract: Pediatric solid tumors have long been known to shed tumor cells, DNA, RNA, and proteins into the blood. Recent technological advances have allowed for improved capture and analysis of these typically scant circulating materials. Efforts… read more here.
Keywords: pediatric solid; liquid biopsies; solid tumors; toward liquid ... See more keywords
Monitoring of RAS mutant clones in plasma of patients with RAS mutant metastatic colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-021-02767-7
Abstract: Some patients with histologically confirmed primary mCRC and mutated RAS reported undetectable RAS mutant clones in plasma after receiving anti-VEGF treatment. The aim was to prospectively assess it with its potential therapeutic implications. RAS mutant… read more here.
Keywords: ras mutant; mutant clones; solid liquid; liquid biopsies ... See more keywords
Liquid biopsies in epilepsy: biomarkers for etiology, diagnosis, prognosis, and therapeutics.
Sign Up to like & getrecommendations! Published in 2021 at "Human cell"
DOI: 10.1007/s13577-021-00624-x
Abstract: Epilepsy is one of the most common diseases of the central nervous system, impacting nearly 50 million people around the world. Heterogeneous in nature, epilepsy presents in children and adults alike. Currently, surgery is one… read more here.
Keywords: biopsies epilepsy; liquid biopsies; etiology diagnosis; etiology ... See more keywords
Quantitative and Qualitative Analysis of Blood-based Liquid Biopsies to Inform Clinical Decision-making in Prostate Cancer.
Sign Up to like & getrecommendations! Published in 2021 at "European urology"
DOI: 10.1016/j.eururo.2020.12.037
Abstract: CONTEXT Genomic stratification can impact prostate cancer (PC) care through diagnostic, prognostic, and predictive biomarkers that aid in clinical decision-making. The temporal and spatial genomic heterogeneity of PC together with the challenges of acquiring metastatic… read more here.
Keywords: liquid biopsies; prostate cancer; based liquid; blood ... See more keywords