Liquid biopsy: a new source of candidate biomarkers in amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.565
Abstract: Noninvasive tests to diagnose and monitor the progression of neurodegenerative disorders have been a challenge for decades. The aim of this study was to explore the feasibility of applying liquid biopsy procedures to patients with… read more here.
Keywords: source; biopsy new; liquid biopsy; amyotrophic lateral ... See more keywords
Artificially Intelligent Nanoarray Detects Various Cancers by Liquid Biopsy of Volatile Markers
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200356
Abstract: Cancer is usually not symptomatic in its early stages. However, early detection can vastly improve prognosis. Liquid biopsy holds great promise for early detection, although it still suffers from many disadvantages, mainly searching for specific… read more here.
Keywords: nanoarray; artificially intelligent; detection; intelligent nanoarray ... See more keywords
Multiplex Digital Methylation‐Specific PCR for Noninvasive Screening of Lung Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202206518
Abstract: There remains tremendous interest in developing liquid biopsy assays for detection of cancer‐specific alterations, such as mutations and DNA methylation, in cell‐free DNA (cfDNA) obtained through noninvasive blood draws. However, liquid biopsy analysis is often… read more here.
Keywords: methylation; multiplex digital; digital methylation; pcr ... See more keywords
Cancer Liquid Biopsy Using Integrated Microfluidic Exosome Analysis Platforms
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Journal"
DOI: 10.1002/biot.201900225
Abstract: Liquid biopsies serve as both powerful noninvasive diagnostic tools for early cancer screening and prognostic tools for monitoring cancer progression and treatment efficacy. Exosomes are promising biomarkers for liquid biopsies, since these nano‐sized extracellular vesicles… read more here.
Keywords: liquid biopsies; integrated microfluidic; liquid biopsy; cancer liquid ... See more keywords
Differences in the genomic profiles of cell‐free DNA between plasma, sputum, urine, and tumor tissue in advanced NSCLC
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.1935
Abstract: Liquid biopsy has provided an efficient way for detection of gene alterations in advanced non‐small‐cell lung cancer (NSCLC). However, the correlation between systematic determination of somatic genomic alterations in liquid biopsy and tumor biopsy still… read more here.
Keywords: tumor tissue; plasma; sputum; liquid biopsy ... See more keywords
Diagnostic performance of various liquid biopsy methods in detecting colorectal cancer: A meta‐analysis
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3276
Abstract: Abstract Liquid biopsy is a promising method in detecting colorectal cancer (CRC). However, previous meta‐analyses only focused on the diagnostic performance of cell‐free DNA (cfDNA). Therefore, we firstly evaluated the overall performance of all liquid… read more here.
Keywords: liquid biopsy; biopsy; biopsy methods; diagnostic performance ... See more keywords
A fluid future for liquid biopsies
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22087
Abstract: O ncologists have dreamed of them for years: noninvasive alternatives to tissue biopsies that can quickly identify tumors by the cells, DNA, or other cell components that they shed into patients’ blood. Now, several promising… read more here.
Keywords: liquid biopsies; fluid future; liquid; future liquid ... See more keywords
Liquid Biopsy for Patient Characterization in Cardiovascular Disease: Verification against Markers of Cytochrome P450 and P‐Glycoprotein Activities
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2576
Abstract: Precision dosing strategies require accounting for between‐patient variability in pharmacokinetics together with subsequent pharmacodynamic differences. Liquid biopsy is a valuable new approach to diagnose disease prior to the appearance of clinical signs and symptoms, potentially… read more here.
Keywords: cardiovascular disease; expression; cytochrome p450; biopsy ... See more keywords
cyc‐DEP: Cyclic immunofluorescence profiling of particles collected using dielectrophoresis
Sign Up to like & getrecommendations! Published in 2022 at "ELECTROPHORESIS"
DOI: 10.1002/elps.202200001
Abstract: Cancer is a highly heterogenous disease that requires precise detection tools and active surveillance methods. Liquid biopsy assays provide an agnostic way to follow the complex trajectory of cancer, providing better patient stratification tools for… read more here.
Keywords: quantification; dep cyclic; cyc dep; liquid biopsy ... See more keywords
Next‐generation liquid biopsy instruments: Challenges and opportunities
Sign Up to like & getrecommendations! Published in 2023 at "ELECTROPHORESIS"
DOI: 10.1002/elps.202200169
Abstract: Conventional cancer diagnosis needs to excise diseased tissue from the patient's body for biopsy, causing severe injury to patients. Liquid biopsy (LB), with the superior advantage of minimal invasiveness, has shown its ability to cancer… read more here.
Keywords: liquid biopsy; instrument; next generation; biopsy ... See more keywords
T‐cell diversification reflects antigen selection in the blood of patients on immune checkpoint inhibition and may be exploited as liquid biopsy biomarker
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Cancer"
DOI: 10.1002/ijc.30549
Abstract: Cancer immunotherapy with antibodies targeting immune checkpoints, such as programmed cell death protein 1 (PD‐1), shows encouraging results, but reliable biomarkers predicting response to this costly and potentially toxic treatment approach are still lacking. To… read more here.
Keywords: response; diversification; inhibition; liquid biopsy ... See more keywords