High-performance liquid chromatographic and subcritical fluid chromatographic separation of α-arylated ß-carboline, N-alkylated tetrahydroisoquinolines and their bioisosteres on polysaccharide-based chiral stationary phases.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of separation science"
DOI: 10.1002/jssc.201900228
Abstract: New, pharmacologically interesting chiral amino compounds, namely stereoisomers of α-hydroxynaphthyl-ß-carboline, benz[d]azepine and benz[c]azepine analogs as well as N-α-hydroxynaphthylbenzyl-substituted isoquinolines were enantioseparated by high-performance liquid chromatographic and subcritical fluid chromatographic (SFC) methods on polysaccharide-based chiral stationary… read more here.
Keywords: liquid chromatographic; separation; high performance; performance liquid ... See more keywords
Liquid Chromatographic Enantiomeric Separation of Chiral Aliphatic Amines Using 2-Hydroxynaphthaldehyde as a Derivatizing Agent on Polysaccharide-Derived Chiral Stationary Phases
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DOI: 10.1007/s10337-018-3560-y
Abstract: A new liquid chromatographic enantiomer separation of chiral amines as 2-hydroxynaphthaldimine derivatives on several coated and immobilized chiral stationary phases (CSPs) derived from polysaccharides is described. 2-Hydroxynaphthaldehyde was introduced as a derivatizing agent for the… read more here.
Keywords: enantiomeric separation; separation; chiral aliphatic; aliphatic amines ... See more keywords
Liquid chromatographic methods coupled to chemometrics: a short review to present the key workflow for the investigation of wine phenolic composition as it is affected by environmental factors
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-020-09681-5
Abstract: The guarantee of wine authenticity arises great concern because of its nutritional and economic importance. Phenolic fingerprints have been used as a source of chemical information for various authentication issues, including botanical and geographical origin,… read more here.
Keywords: environmental factors; wine; chromatographic methods; investigation ... See more keywords
A new rapid and economic liquid chromatographic method for simultaneous determination of meglitinides with metformin: application in the presence of metformin and repaglinide impurities and related compounds
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-017-1209-7
Abstract: A new liquid chromatographic method was developed for simultaneous determination of the widely used oral antidiabetic, metformin hydrochloride with antidiabetics comprising the meglitinides class in bulk, laboratory-prepared mixtures and pharmaceutical products. It was applied in… read more here.
Keywords: presence; determination; metformin; method ... See more keywords
Investigating the Effect of Column Geometry on Separation Efficiency using 3D Printed Liquid Chromatographic Columns Containing Polymer Monolithic Phases.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b03778
Abstract: Effect of column geometry on the liquid chromatographic separations using 3D printed liquid chromatographic columns with in-column polymerized monoliths has been studied. Three different liquid chromatographic columns were designed and 3D printed in titanium as… read more here.
Keywords: column; effect column; geometry; liquid chromatographic ... See more keywords
Tunable liquid chromatographic separation of H/D isotopologues enabled by aromatic π interactions.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b05672
Abstract: We report hydrogen/deuterium (H/D) isotope effects based on weak intermolecular interactions with polar functional groups and aromatic rings in liquid chromatography (LC). Various LC experiments with different aromatic analytes, separation media, and non-polar mobile phases… read more here.
Keywords: tunable liquid; chromatographic separation; separation; interaction ... See more keywords
Accurate and Sensitive Reverse Phase High-Performance Liquid Chromatographic Determination of Arbutin in Blueberries and Characterization of Its Stability in Simulated Gastric Fluid and under Ultraviolet Irradiation
Sign Up to like & getrecommendations! Published in 2020 at "Analytical Letters"
DOI: 10.1080/00032719.2019.1710523
Abstract: Abstract In this study, arbutin, an antibacterial skin-whitening agent was identified and quantified in blueberry samples using a developed high-performance liquid chromatographic (HPLC) method. The best instrumental conditions were obtained by performing step-by-step optimization studies.… read more here.
Keywords: gastric fluid; liquid chromatographic; high performance; fluid ultraviolet ... See more keywords
Optimization of High-Performance Liquid Chromatographic Method Using Central Composite Design for the Simultaneous Estimation of Ciprofloxacin and Loteprednol.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmac016
Abstract: A simple, rapid, precise and accurate stability indicating high-performance liquid chromatographic (HPLC) method was developed for simultaneous quantification of Ciprofloxacin (CIP) and Loteprednol (LOT) along with their forced degradation products using central composite design (CCD)… read more here.
Keywords: high performance; method; liquid chromatographic; using central ... See more keywords
Liquid Chromatographic Chiral Separation of Acenocoumarol and Its Hemiketal Form.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmx061
Abstract: Acenocoumarol, an anticoagulant drug, was separated successfully using polysaccharide-based chiral stationary phases columns namely Cellulose Chiralpak® IB and Chiralcel® OD, using various normal mobile phases by high-performance liquid chromatography. However, the appearance of four well… read more here.
Keywords: liquid chromatographic; hemiketal form; acenocoumarol; chromatographic chiral ... See more keywords
A Validated Liquid Chromatographic Method for Berberine Analysis in Tissue and Application
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Analytical Chemistry"
DOI: 10.1155/2020/8892696
Abstract: Simple and rapid high-performance liquid chromatography methods were developed for the determination of berberine (BB) in various rat tissues so as to evaluate a P-gp inhibitor, glycyrrhetinic acid (GA), on BB's oral bioavailability. Acetonitrile was… read more here.
Keywords: validated liquid; tissue; method berberine; chromatographic method ... See more keywords
Development and Validation of a Liquid Chromatographic Method for Aroylhydrazones at Hydrolytic Conditions
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DOI: 10.2174/1573412916666191231094046
Abstract: The indole-containing aroylhydrazone derivatives 3a-c with potent antimycobacterial activity against a referent strain M. tuberculosis H37Rv and low cytotoxicity were evaluated for their stability via the precise and accurate HPLC analytical method in aqueous media… read more here.
Keywords: liquid chromatographic; development validation; development; method ... See more keywords