Liraglutide treatment reduced interleukin‐6 in adults with type 1 diabetes but did not improve established autonomic or polyneuropathy
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.14063
Abstract: Type 1 diabetes can be complicated with neuropathy that involves immune‐mediated and inflammatory pathways. Glucagon‐like peptide‐1 receptor agonists such as liraglutide, have shown anti‐inflammatory properties, and thus we hypothesized that long‐term treatment with liraglutide induced… read more here.
Keywords: type; type diabetes; treatment reduced; liraglutide treatment ... See more keywords
Effects of liraglutide on cardiovascular risk biomarkers in patients with type 2 diabetes and albuminuria: A sub‐analysis of a randomized, placebo‐controlled, double‐blind, crossover trial
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DOI: 10.1111/dom.12884
Abstract: We assessed the effects of liraglutide treatment on five cardiovascular risk biomarkers, reflecting different pathophysiology: tumour necrosis factor (TNF)‐α; soluble urokinase plasminogen activator receptor (suPAR); mid‐regional pro‐adrenomedullin (MR‐proADM); mid‐regional pro‐atrial natriuretic peptide (MR‐proANP); and copeptin,… read more here.
Keywords: liraglutide treatment; type diabetes; cardiovascular risk; placebo ... See more keywords
Liraglutide treatment attenuates inflammation markers in the cardiac, cerebral and renal microvasculature in streptozotocin‐induced diabetic rats
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Clinical Investigation"
DOI: 10.1111/eci.13807
Abstract: Diabetes mellitus (DM) induces cardiac and cerebral microvascular dysfunction via increased glycation, oxidative stress and endothelial activation. Liraglutide, a glucagon‐like peptide‐1 analogue, inhibited NOX2 and adhesion molecules in isolated endothelial cells. Here, we have studied… read more here.
Keywords: renal microvasculature; cardiac cerebral; diabetic rats; cerebral renal ... See more keywords
Effect of liraglutide on neural and peripheral markers of metabolic function during antipsychotic treatment in rats
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DOI: 10.1177/0269881120981377
Abstract: Background: Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that prevents metabolic side effects of the antipsychotic drugs (APDs) olanzapine and clozapine through unknown mechanisms. Aim: This study aimed to investigate the effect of chronic… read more here.
Keywords: neural peripheral; clozapine; liraglutide treatment; treatment ... See more keywords
Liraglutide for the treatment of obesity: Analyzing published reviews.
Sign Up to like & getrecommendations! Published in 2019 at "Current pharmaceutical design"
DOI: 10.2174/1381612825666190701155737
Abstract: BACKGROUND Several drugs have been currently approved for the treatment of obesity. The pharmacokinetic of liraglutide, as well as for the treatment of type 2 diabetes mellitus, have been widely described. OBJECTIVE To analyze the… read more here.
Keywords: liraglutide treatment; treatment; treatment obesity; systematic reviews ... See more keywords
Case Report: Liraglutide for Weight Management in Beckwith-Wiedemann Syndromic Obesity
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.687918
Abstract: Genetic obesity, including syndromic and non-syndromic forms, represents a minority of cases compared to essential obesity but gene dysregulations lead to complex clinical conditions that make their management particularly difficult. Among them, Beckwith-Wiedemann syndrome (BWS)… read more here.
Keywords: liraglutide treatment; endocrinology; case; management ... See more keywords
Feasibility, Adherence and Efficacy of Liraglutide Treatment in a Sample of Individuals With Mood Disorders and Obesity
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2018.00784
Abstract: Background: Liraglutide is a once-daily injectable medication approved for the treatment of obesity. Hereby we report the feasibility, adherence and efficacy of liraglutide treatment in a sample of individuals with mood disorders and obesity. Methods… read more here.
Keywords: sample; efficacy liraglutide; liraglutide treatment; treatment ... See more keywords
Liraglutide Treatment Ameliorates Neurotoxicity Induced by Stable Silencing of Pin1
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DOI: 10.3390/ijms20205064
Abstract: Post-translational modulation of peptidylprolyl isomerase Pin1 might link impaired glucose metabolism and neurodegeneration, being Pin1 effectors target for the glucagon-Like-Peptide1 analog liraglutide. We tested the hypotheses in Pin1 silenced cells (SH-SY5Y) treated with 2-deoxy-d-glucose (2DG)… read more here.
Keywords: cell viability; liraglutide treatment; pin1 silencing; treatment ameliorates ... See more keywords