Developmental downregulation of LIS1 expression limits axonal extension and allows axon pruning
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DOI: 10.1242/bio.025999
Abstract: ABSTRACT The robust axonal growth and regenerative capacities of young neurons decrease substantially with age. This developmental downregulation of axonal growth may facilitate axonal pruning and neural circuit formation but limits functional recovery following nerve… read more here.
Keywords: axonal extension; lis1 expression; developmental downregulation;