ATP1A3-related epilepsy: Report of seven cases and literature-based analysis of treatment response
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2020.01.041
Abstract: ATP1A3 related disease is a clinically heterogeneous condition currently classified as alternating hemiplegia of childhood, rapid-onset dystonia-parkinsonism and cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss. Recently, it has become apparent that… read more here.
Keywords: response; treatment; related epilepsy; atp1a3 related ... See more keywords
Literature-based prediction of novel drug indications considering relationships between entities.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c7mb00020k
Abstract: There have been many attempts to identify and develop new uses for existing drugs, which is known as drug repositioning. Among these efforts, text mining is an effective means of discovering novel knowledge from a… read more here.
Keywords: phenotype; phenotype associations; drug phenotype; drug repositioning ... See more keywords
Literature-Based Strategies for Clinical Fellow Mentorship.
Sign Up to like & getrecommendations! Published in 2020 at "Seminars in speech and language"
DOI: 10.1055/s-0040-1713784
Abstract: In the field of communication sciences and disorders, some research and guidance exist on clinical fellowship supervision for the mentor; however, there is a dearth of literature on clinical fellowship supervision from the perspective of… read more here.
Keywords: literature; clinical fellowship; mentorship; clinical fellow ... See more keywords
Literature-based discovery of new candidates for drug repurposing
Sign Up to like & getrecommendations! Published in 2017 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbw030
Abstract: Drug development is an expensive and time-consuming process; these could be reduced if the existing resources could be used to identify candidates for drug repurposing. This study sought to do this by text mining a… read more here.
Keywords: candidates drug; literature; drug repurposing; drug ... See more keywords
Exploring automatic inconsistency detection for literature-based gene ontology annotation
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac230
Abstract: Abstract Motivation Literature-based gene ontology annotations (GOA) are biological database records that use controlled vocabulary to uniformly represent gene function information that is described in the primary literature. Assurance of the quality of GOA is… read more here.
Keywords: based gene; literature based; inconsistency; ontology ... See more keywords
Literature-based discovery: addressing the issue of the subpar evaluation methodology
Sign Up to like & getrecommendations! Published in 2023 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btad090
Abstract: The author argues that the field of Literature-Based Discovery (LBD) is built on sand, due to a lack of appropriate evaluation method. The field is considered mature and a healthy number of papers are published… read more here.
Keywords: evaluation; literature based; issue; methodology ... See more keywords
MeSHDD: Literature-based drug-drug similarity for drug repositioning
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Medical Informatics Association : JAMIA"
DOI: 10.1093/jamia/ocw142
Abstract: Objective: Drug repositioning is a promising methodology for reducing the cost and duration of the drug discovery pipeline. We sought to develop a computational repositioning method leveraging annotations in the literature, such as Medical Subject… read more here.
Keywords: drug repositioning; similarity; drug; literature based ... See more keywords
Exploring literature‐based definitions of hypotony following glaucoma filtration surgery and the impact on clinical outcomes
Sign Up to like & getrecommendations! Published in 2018 at "Acta Ophthalmologica"
DOI: 10.1111/aos.13601
Abstract: To highlight the variations in published definitions of hypotony and their impact on reported clinical outcomes. To propose a revised definition, focusing on clinically significant hypotony (CH). read more here.
Keywords: clinical outcomes; based definitions; impact; definitions hypotony ... See more keywords
Neural networks for open and closed Literature-based Discovery
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0232891
Abstract: Literature-based Discovery (LBD) aims to discover new knowledge automatically from large collections of literature. Scientific literature is growing at an exponential rate, making it difficult for researchers to stay current in their discipline and easy… read more here.
Keywords: lbd; literature; based discovery; neural networks ... See more keywords