In the literature: February 2021
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DOI: 10.1016/j.esmoop.2021.100061
Abstract: BRCA1 is a tumor-suppressor gene that encodes proteins involved in the repair of DNA double-strand breaks by way of the homologous recombination repair pathway. BRCA1 mutations occur in approximately 5% of breast cancer (BC) patients.… read more here.
Keywords: literature february; anti csf1r; february 2021; treatment ... See more keywords
In the literature: February 2017
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DOI: 10.1136/esmoopen-2017-000171
Abstract: The hallmark of mantle cell lymphoma (MCL) is the t(11;14)(q13,q32) translocation, which leads to the juxtaposition of CCDN1 to the IgH promoter locus, resulting in cyclin D1 overexpression. However, studies from transgenic mouse show that… read more here.
Keywords: mcl; literature february; methylation; february 2017 ... See more keywords
In the literature: February 2018
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DOI: 10.1136/esmoopen-2018-000322
Abstract: Non-invasive liquid biopsies may transform the management of patients with cancer. Circulating tumour DNA (ctDNA) derived from cancer cells can be identified in most patients with advanced cancer, representing a potential non-invasive source of tumour… read more here.
Keywords: literature february; ctdna; tumour dna; residual disease ... See more keywords