Drug repurposing by integrated literature mining and drug-gene-disease triangulation.
Sign Up to like & getrecommendations! Published in 2017 at "Drug discovery today"
DOI: 10.1016/j.drudis.2016.10.008
Abstract: Drug design is expensive, time-consuming and becoming increasingly complicated. Computational approaches for inferring potentially new purposes of existing drugs, referred to as drug repositioning, play an increasingly important part in current pharmaceutical studies. Here, we… read more here.
Keywords: literature mining; disease triangulation; drug gene; drug ... See more keywords
Integration of microarray data and literature mining identifies a sex bias in DPP4+CD4+ T cells in HIV-1 infection
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DOI: 10.1371/journal.pone.0239399
Abstract: HIV-1 infection exhibits a significant sex bias. This study aimed at identifying and examining lymphocyte associated sex differences in HIV-1 pathogenesis using a data-driven approach. To select targets for investigating sex differences in lymphocytes, data… read more here.
Keywords: hiv infection; literature mining; sex bias; sex differences ... See more keywords