Articles with "lithium induced" as a keyword



Lithium‐Induced Optimization Mechanism for an Ultrathin‐Strut Biodegradable Zn‐Based Vascular Scaffold

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Published in 2023 at "Advanced Materials"

DOI: 10.1002/adma.202301074

Abstract: To reduce incidences of in‐stent restenosis and thrombosis, the use of a thinner‐strut stent has been clinically proven to be effective. Therefore, the contemporary trend is toward the use of ultrathin‐strut (≤70 µm) designs for… read more here.

Keywords: ultrathin strut; induced optimization; optimization mechanism; lithium induced ... See more keywords
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Lithium‐induced electrocardiographic changes: A complete review

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Published in 2017 at "Clinical Cardiology"

DOI: 10.1002/clc.22822

Abstract: Lithium has been used for the treatment of bipolar disorder for more than 6 decades. Reports of cardiac side effects resulting in both benign electrocardiographic (ECG) changes and near fatal arrhythmias have been reported in… read more here.

Keywords: electrocardiographic changes; changes complete; induced electrocardiographic; lithium ... See more keywords

Role of Oxidative Stress in Lithium-Induced Nephropathy

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Published in 2019 at "Biological Trace Element Research"

DOI: 10.1007/s12011-018-1617-2

Abstract: Long-term lithium treatment was associated with chronic kidney disease and renal failure although the underlying pathogenic mechanisms are not certainty known. The aim of this study was to evaluate changes in oxidative stress measures as… read more here.

Keywords: pathogenic mechanisms; lithium; induced nephropathy; lithium induced ... See more keywords
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Lithium-induced downbeat nystagmus

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Published in 2017 at "American Journal of Ophthalmology Case Reports"

DOI: 10.1016/j.ajoc.2017.06.012

Abstract: We report the case of a 76-year old lady under lithium carbonate for a bipolar disorder who presented with a suspected optic neuritis. A typical lithium-induced downbeat nystagmus was observed. Discontinuation of lithium therapy resulted… read more here.

Keywords: ophthalmology; induced downbeat; downbeat nystagmus; lithium ... See more keywords

RNA-Seq and protein mass spectrometry in microdissected kidney tubules reveal signaling processes initiating lithium-induced nephrogenic diabetes insipidus.

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Published in 2019 at "Kidney international"

DOI: 10.1016/j.kint.2019.02.015

Abstract: Lithium salts, used for treating bipolar disorder, frequently induce nephrogenic diabetes insipidus (NDI) thereby limiting therapeutic success. NDI is associated with loss of expression of the gene coding for the molecular water channel, aquaporin-2, in… read more here.

Keywords: nephrogenic diabetes; lithium induced; diabetes insipidus; rna seq ... See more keywords

Investigation of the effects of silymarin and vitamin C on kidney damage and aquaporin-2 downregulation in lithium-induced nephrogenic diabetes insipidus in rats

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Published in 2025 at "Drug and Chemical Toxicology"

DOI: 10.1080/01480545.2025.2450475

Abstract: Abstract Although lithium (LIT) therapy is key in managing bipolar disorder long-term, prolonged use significantly contributes to acquired Nephrogenic Diabetes Insipidus (NDI). This study examined whether combining Silymarin (SIL) with Vitamin C (Vit C) enhances… read more here.

Keywords: lithium; nephrogenic diabetes; induced nephrotoxicity; diabetes insipidus ... See more keywords

Lithium-induced ciliary lengthening sparks Arp2/3 complex–dependent endocytosis

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Published in 2022 at "Molecular Biology of the Cell"

DOI: 10.1091/mbc.e22-06-0219

Abstract: Ciliary length is highly regulated across cell types, but this tight regulation can be disrupted by lithium, which causes ciliary elongation across cell types and organisms. Here, we use the powerful ciliary model Chlamydomonas reinhardtii… read more here.

Keywords: elongation; lithium; arp2 complex; lithium induced ... See more keywords

Lithium-Induced Ekbom Syndrome in a Case of Juvenile Bipolar Mood Disorder.

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Published in 2020 at "American Journal of Therapeutics"

DOI: 10.1097/mjt.0000000000001187

Abstract: To the Editor: A 13-year-old Iraqi male youngster, with a positive maternal history of bipolarity, was admitted to our inpatient facility for escalating aggression and socially flouting behaviors. He had a 5-day history of decreased… read more here.

Keywords: lithium induced; mood; induced ekbom; lithium ... See more keywords

Lack of renal NHE1 exacerbates lithium‐induced nephrogenic diabetes insipidus

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Published in 2025 at "Acta Physiologica"

DOI: 10.1111/apha.70029

Abstract: The sodium‐hydrogen exchanger isoform 1 (NHE1) is important for transepithelial Na+/H+ transport, intracellular pH, and cell volume regulation. NHE1 also transports Li+, preferably compared to NHE3, and the lack of NHE3 does not affect renal… read more here.

Keywords: nhe1; lack renal; lithium induced; exacerbates lithium ... See more keywords

Lysine acetylation of aquaporin-3 does not improve lithium-induced nephrogenic diabetes insipidus.

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Published in 2025 at "Canadian journal of physiology and pharmacology"

DOI: 10.1139/cjpp-2025-0177

Abstract: Aquaporin-3 (AQP3) is expressed in the basolateral membrane of the renal principal cell contributing to vasopressin-mediated water reabsorption and urine concentration. We reported that post-translational acetylation of lysine 282 of AQP3 promotes water permeability. In… read more here.

Keywords: nephrogenic diabetes; water; induced nephrogenic; diabetes insipidus ... See more keywords

Various endurance training intensities improve GFR and Up-regulate AQP2/GSK3β in lithium-induced nephropathic rats

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Published in 2025 at "BMC Nephrology"

DOI: 10.1186/s12882-025-03997-5

Abstract: Lithium is extensively used for mood stabilization in bipolar disorder, but its long-term use can lead to nephrotoxicity, characterized by a reduction in glomerular filtration rate (GFR) and potential progression to end-stage renal disease (ESRD).… read more here.

Keywords: lithium; aqp2; lithium induced; endurance training ... See more keywords