The Pharmacogenomics of Bipolar Disorder Study: A Combined Analysis Of Ips Neuronal Expression And Gwas Data Identifies Cbarp And Card19 As Associated With Lithium Response
Sign Up to like & getrecommendations! Published in 2017 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2016.09.575
Abstract: Background Lithium was the first mood stabilizing medication and remains the most effective. A variety of data argue that lithium responsive bipolar disorder may be genetically distinct and hence lithium response may be a powerful… read more here.
Keywords: response; lithium response; expression; lithium ... See more keywords
Prediction of lithium response using clinical data
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DOI: 10.1111/acps.13122
Abstract: Promptly establishing maintenance therapy could reduce morbidity and mortality in patients with bipolar disorder. Using a machine learning approach, we sought to evaluate whether lithium responsiveness (LR) is predictable using clinical markers. read more here.
Keywords: using clinical; response using; prediction lithium; lithium response ... See more keywords
Whole Genome Expression Analyses of miRNAs and mRNAs Suggest the Involvement of miR-320a and miR-155-3p and their Targeted Genes in Lithium Response in Bipolar Disorder
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DOI: 10.3390/ijms20236040
Abstract: Lithium is the mainstay in the maintenance of bipolar disorder (BD) and the most efficacious pharmacological treatment in suicide prevention. Nevertheless, its use is hampered by a high interindividual variability and important side effects. Genetic… read more here.
Keywords: targeted genes; mir 155; mir; lithium response ... See more keywords