Haploinsufficiency of Cyfip2 Causes Lithium-Responsive Prefrontal Dysfunction.
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DOI: 10.1002/ana.25827
Abstract: OBJECTIVE Genetic variants of the cytoplasmic FMR1-interacting protein 2 (CYFIP2) encoding an actin-regulatory protein are associated with brain disorders, including intellectual disability and epilepsy. However, specific in vivo neuronal defects and potential treatments for CYFIP2-associated… read more here.
Keywords: adult cyfip2; prefrontal dysfunction; lithium responsive; cyfip2 mice ... See more keywords