Lithium treatment in the era of personalized medicine
Sign Up to like & getrecommendations! Published in 2020 at "Drug Development Research"
DOI: 10.1002/ddr.21660
Abstract: In 1949, an Australian psychiatrist, John Cade, reported on the antimanic efficacy of lithium carbonate, which is regarded as an introduction of lithium into contemporary psychiatry. Since the 1960s, lithium has been a precursor of… read more here.
Keywords: medicine; lithium treatment; mood; lithium ... See more keywords
Lithium treatment and mechanisms of aging
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Psychiatry"
DOI: 10.1038/s41380-018-0024-6
Abstract: Lithium—a light metal named after the Greek word “lithos,” meaning “stone”—has been extensively used, in various salt forms, in the treatment of mood disorders for over half a century. During this stretch of time, a… read more here.
Keywords: treatment; mortality; lithium treatment; effect ... See more keywords
Lithium treatment and human hippocampal neurogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Translational Psychiatry"
DOI: 10.1038/s41398-021-01695-y
Abstract: Lithium is a first-line treatment for bipolar disorder, where it acts as a mood-stabilizing agent. Although its precise mechanism remains unclear, neuroimaging studies have shown that lithium accumulates in the hippocampus and that chronic use… read more here.
Keywords: neurogenesis; treatment human; lithium treatment; human hippocampal ... See more keywords
Lithium Treatment in Children and Adolescents.
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacopsychiatry"
DOI: 10.1055/a-0575-4179
Abstract: INTRODUCTION There is a resurgence of interest in lithium treatment of bipolar disorders in part related to its unique anti-suicidal and neuroprotective effects. METHODS This is a narrative review of key studies pertaining to the… read more here.
Keywords: treatment pediatric; treatment; lithium treatment; lithium ... See more keywords
Molecular Signatures of Lithium Treatment: Current Knowledge.
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacopsychiatry"
DOI: 10.1055/a-0650-4820
Abstract: Lithium (Li) is the key mood stabilizer in the prevention of mood recurrences and suicide in bipolar disorders. However, only one-third of patients become asymptomatic with Li treatment, and to date, no clinical markers can… read more here.
Keywords: signatures lithium; treatment; current knowledge; lithium treatment ... See more keywords
No Connection between Long-Term Lithium Treatment and Antithyroid Antibodies.
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacopsychiatry"
DOI: 10.1055/a-0838-6062
Abstract: INTRODUCTION The studies on the effect of lithium treatment on antithyroid antibodies showed either a higher concentration of these antibodies in patients receiving lithium compared to those lithium-naive or no difference between these groups. In… read more here.
Keywords: connection long; antithyroid antibodies; treatment antithyroid; lithium treatment ... See more keywords
Efficacy and tolerability of lithium for the treatment of acute mania in children with bipolar disorder: A systematic review
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DOI: 10.1111/bdi.12690
Abstract: To assess the efficacy and tolerability of lithium for the treatment of acute mania in children and adolescent diagnosed with bipolar disorder. read more here.
Keywords: acute mania; lithium treatment; treatment acute; mania children ... See more keywords
Lithium treatment for chronic traumatic encephalopathy: A proposal
Sign Up to like & getrecommendations! Published in 2019 at "Bipolar Disorders"
DOI: 10.1111/bdi.12757
Abstract: Chronic traumatic encephalopathy (CTE) is a diagnosis recently discovered and described in the context of American football. It is a a neurodegenerative disease that is a consequence of repetitive brain injury such as concussion. Such… read more here.
Keywords: traumatic encephalopathy; lithium treatment; encephalopathy proposal; chronic traumatic ... See more keywords
Clinical manifestations of schizophrenia in four patients with variants in voltage‐gated calcium channel‐encoding genes: a case series
Sign Up to like & getrecommendations! Published in 2022 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.13494
Abstract: Existing data indicate that lithium treatment may reduce the risk of car-diovascular diseases in patients with bipolar disorder (BD). 1 – 3 Our recent pilot study demonstrated that longer lithium exposure was associated with favorable… read more here.
Keywords: schizophrenia four; lithium treatment; manifestations schizophrenia; lithium ... See more keywords
Starting lithium in patients with compromised renal function – is it wise?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Psychopharmacology"
DOI: 10.1177/0269881120936541
Abstract: Background: Little is known of the risks involved for patients who, at the start of lithium treatment, already have compromised renal function. Aims: To assess the risk of developing severe renal impairment (chronic kidney disease… read more here.
Keywords: lithium treatment; renal function; lithium; compromised renal ... See more keywords
Comparing measurements of lithium treatment efficacy in people with bipolar disorder: systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2023 at "BJPsych Open"
DOI: 10.1192/bjo.2023.64
Abstract: Background Lithium has long been recognised as an effective treatment for bipolar disorder. Its relative efficacy has been measured with a diverse range of clinical outcomes, resulting in differences in efficacy reporting that have not… read more here.
Keywords: lithium treatment; efficacy; people bipolar; bipolar disorder ... See more keywords