Effects of lithium and valproate on behavioral parameters and neurotrophic factor levels in an animal model of mania induced by paradoxical sleep deprivation.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2019.09.003
Abstract: The present study aimed to evaluate the effects of treatment with lithium (Li) and valproate (VPA) on behaviors and brain BDNF, NGF, NT-3, NT-4 and GDNF levels in mice submitted to paradoxical sleep deprivation (PSD),… read more here.
Keywords: sleep deprivation; animal model; model mania; psd ... See more keywords
Lithium and Valproate in Bipolar Disorder: From International Evidence-based Guidelines to Clinical Predictors
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Psychopharmacology and Neuroscience"
DOI: 10.9758/cpn.2022.20.3.403
Abstract: Since decades, lithium and valproate remain the pharmacological cornerstone to treat bipolar disorder. Different response patterns occur according to the phases of illness. At same time, individual pretreatment variables may concur to determine a specific… read more here.
Keywords: bipolar disorder; valproate bipolar; lithium valproate;