Hybrid de novo genome assembly of red gromwell (Lithospermum erythrorhizon) reveals evolutionary insight into shikonin biosynthesis
Sign Up to like & getrecommendations! Published in 2020 at "Horticulture Research"
DOI: 10.1038/s41438-020-0301-9
Abstract: Lithospermum erythrorhizon (red gromwell; zicao) is a medicinal and economically valuable plant belonging to the Boraginaceae family. Roots from L. erythrorhizon have been used for centuries based on the antiviral and wound-healing properties produced from… read more here.
Keywords: lithospermum erythrorhizon; shikonin alkannin; red gromwell; shikonin ... See more keywords
A Cytosol-Localized Geranyl Diphosphate Synthase from Lithospermum erythrorhizon and Its Molecular Evolution1[OPEN]
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DOI: 10.1104/pp.19.00999
Abstract: A unique cytosol-localized geranyl diphosphate synthase supporting a large production of shikonin has evolved from farnesyl diphosphate synthase in Lithospermum erythrorhizon. Geranyl diphosphate (GPP) is the direct precursor of all monoterpenoids and is the prenyl… read more here.
Keywords: synthase; lithospermum erythrorhizon; geranyl diphosphate; diphosphate ... See more keywords
Network Pharmacology Revealed the Mechanisms of Action of Lithospermum erythrorhizon Sieb on Atopic Dermatitis
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DOI: 10.2147/ccid.s403736
Abstract: Aim The application of network analysis algorithms promoted the development of network pharmacology. This study aimed to combine network pharmacology and signed random walk with restart (SRWR) to reveal the mechanism by which Lithospermum erythrorhizon… read more here.
Keywords: erythrorhizon sieb; lithospermum erythrorhizon; pharmacology; network pharmacology ... See more keywords
Revealing Potential Bioactive Compounds and Mechanisms of Lithospermum erythrorhizon against COVID-19 via Network Pharmacology Study
Sign Up to like & getrecommendations! Published in 2022 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb44050123
Abstract: Lithospermum erythrorhizon (LE) is known in Korean traditional medicine for its potent therapeutic effect and antiviral activity. Currently, coronavirus (COVID-19) disease is a developing global pandemic that can cause pneumonia. A precise study of the… read more here.
Keywords: lithospermum erythrorhizon; bioactive compounds; pharmacology; covid ... See more keywords