Unveiling the multitarget mechanism of Liuwei Dihuang decoction in autism spectrum disorder via network pharmacology and molecular docking.
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DOI: 10.1038/s41598-025-28204-1
Abstract: Liuwei Dihuang decoction (LW) is used for paediatric autism spectrum disorders (ASD) treatment, but its mechanism of action is unclear. This study aims to provide clinical evidence for LW in treating ASD in children and… read more here.
Keywords: molecular docking; liuwei dihuang; pharmacology; mechanism ... See more keywords
Prediction of network pharmacology and molecular docking-based strategy to determine potential pharmacological mechanism of Liuwei Dihuang pill against tinnitus
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DOI: 10.1097/md.0000000000031711
Abstract: Background: Liuwei Dihuang Pill is widely used to treat tinnitus in China. However, the underlying mechanism of Liuwei Dihuang Pill in treating tinnitus still remains unclear. Objective: To explore the potential pharmacological mechanism of Liuwei… read more here.
Keywords: pharmacology; dihuang pill; liuwei dihuang; tinnitus ... See more keywords
Efficacy of Co-administration of Liuwei Dihuang Pills and Ginkgo Biloba Tablets on Albuminuria in Type 2 Diabetes: A 24-Month, Multicenter, Double-Blind, Placebo-Controlled, Randomized Clinical Trial
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DOI: 10.3389/fendo.2019.00100
Abstract: Purpose: We investigated the effects of Traditional Chinese Medicine (TCM) on the occurrence and progression of albuminuria in patients with type 2 diabetes. Methods: In this randomized, double-blind, multicenter, controlled trial, we enrolled 600 type… read more here.
Keywords: ginkgo biloba; dihuang pills; trial; type diabetes ... See more keywords
Modified Liuwei Dihuang Decoction Ameliorates Oligoasthenozoospermia in Mice via Modulation of the PI3K/AKT/Nrf2 Signaling Pathway
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DOI: 10.3390/ph18091363
Abstract: Background: Oligoasthenozoospermia (OA) is a common cause of male infertility. Modified Liuwei Dihuang Decoction (MLWDH) is an improved version of Liuwei Dihuang Decoction (LWDH), a traditional Chinese medicine prescription, which has demonstrated significant therapeutic effects… read more here.
Keywords: liuwei dihuang; pharmacology; akt nrf2; dihuang decoction ... See more keywords
Inhibition of N-methyl-N-nitrosourea-induced gastric tumorigenesis by Liuwei Dihuang Pill in db/db mice
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DOI: 10.3748/wjg.v23.i23.4233
Abstract: AIM To investigate the inhibitory effect of Liuwei Dihuang Pill (LDP) on gastric tumorigenesis induced by N-methyl-N-nitrosourea (MNU) in diabetic mice. METHODS Four-week-old mice were divided into four groups: A, 12 db/m mice treated with… read more here.
Keywords: gastric tumorigenesis; mice treated; mice; dihuang pill ... See more keywords